Results 61 to 70 of about 255,935 (312)

Sputum biomarkers in IPF: Evidence for raised gene expression and protein level of IGFBP-2, IL-8 and MMP-7

PLoS ONE, 2017
Background Idiopathic pulmonary fibrosis (IPF) is a rare lung disease of unknown origin leading rapidly to death. This paper addresses the issue of whether sputum induction is a suitable tool to study respiratory tract inflammation and potential ...
J. Guiot, M. Henket, J. Corhay, C. Moermans, R. Louis   +4 more
semanticscholar   +1 more source

Lung Cancer Patients Display Increased Expression of Bovine Meat and Milk Factor (BMMF) Proteins in Peritumor Alveolar Macrophages

International Journal of Cancer, EarlyView.
Plasmid‐like DNA sequences frequently found in bovine milk and serum have been proposed as infectious agents promoting indirect carcinogenesis. This multi‐omics study detected immune cells positive for these bovine meat and milk factors (BMMFs) in patients with lung cancer, with BMMF expression inversely correlated with smoking intensity.
Nives Cecere, Kristina Alikhanyan, Claudia Ernst, Lisa Häfele, Lars Feuerbach, Imke Grewe, Sumen Siqin, Karin Gunst, Gunjan Shukla, Veronika Frehtman, Claudia Tessmer, Florian Eichhorn, Michael Allgäuer, Alexander Brobeil, Ilse Hofmann, Barbara Leuchs, Marc A. Schneider, Timo Bund   +17 more
wiley   +1 more source

The SNP rs13147758 in the HHIP Gene Is Associated With COPD Susceptibility, Serum, and Sputum Protein Levels in Smokers

Frontiers in Genetics, 2020
BackgroundGenetic association studies have identified single nucleotide polymorphisms (SNPs) related to chronic obstructive pulmonary disease (COPD) susceptibility.
Alejandro Ortega-Martínez, Alejandro Ortega-Martínez, Gloria Pérez-Rubio, Enrique Ambrocio-Ortiz, Karol J. Nava-Quiroz, Rafael de Jesus Hernández-Zenteno, Edgar Abarca-Rojano, Sebastián Rodríguez-Llamazares, Andrea Hernández-Pérez, Leonor García-Gómez, Alejandra Ramírez-Venegas, Ramcés Falfán-Valencia   +11 more
doaj   +1 more source

Strongyloides stercoralis in sputum [PDF]

QJM, 2013
A 68-year-old man had the initial presentation of poor appetite, productive cough for 1 month and body weight loss for 10 kg in half a year. His medical history included bladder cancer and diabetes mellitus. Laboratory testing demonstrated a white blood count of 15 800 cells/μl with a neutrophil count of 11 060 (70%) cells/μl and eosinophil count of ...
C-U, Cheong, S-J, Gau, C-C, Lai
openaire   +2 more sources

High‐Throughput Geocoding to Assess Short‐Term Air Pollution in Correlation With Mortality in a French Cancer Patient Cohort

International Journal of Cancer, EarlyView.
Although chronic air pollution exposure is linked to lung cancer mortality, the short‐term effects of fluctuating air quality on overall cancer mortality remain uncertain. Here, the authors applied geomatics and machine‐learning models to retrospectively examine possible associations between 31‐day pollution exposure and mortality in a French cancer ...
Loice Pokam, Joséphine Bocquet, Nadia Hégarat, Julie Perlbarg‐Samson, Thomas Balezeau, Maud Milder, Bastien Rance, Hector Countouris, Julien Guerin, Flavien Gilles, Jean Gaudart, Nicolas Girard, Clémence Basse   +12 more
wiley   +1 more source

Comparison of sputum collection methods for tuberculosis diagnosis: a systematic review and pairwise and network meta-analysis

Lancet Global Health, 2017
Summary Background The performance of laboratory tests to diagnose pulmonary tuberculosis is dependent on the quality of the sputum sample tested. The relative merits of sputum collection methods to improve tuberculosis diagnosis are poorly characterised.
S. Datta, L. Shah, R. Gilman, C. Evans
semanticscholar   +1 more source

Safety of sputum induction [PDF]

European Respiratory Journal, 2002
One of the most important recent advances in the investigation of airway inflammation has been the introduction of sputum induction by inhalation of an aerosol of hypertonic saline, by Pin et al. 1 in 1992, to directly obtain airway secretions in asthma. This method has a number of advantages over invasive methods.
Pizzichini, E., Pizzichini, M. M. M., Leigh, R., Djukanović, R., Sterk, P. J.   +4 more
openaire   +3 more sources

Exposure to micro‐ and nano‐plastics: From human internal burden to systems‐level health‐risk interpretation

iMeta, EarlyView.
Micro‐ and nano‐plastics (MNPs) can enter the human body through inhalation, ingestion, contact with consumer products, and iatrogenic routes. The clinical relevance of MNP exposure should be interpreted at three levels: barrier interaction, cellular stress, and system‐level disruption, with key mechanisms including oxidative stress, mitochondrial ...
Chen Tu, Jie Yang, Jingyi Liao, Rongkui Hu, Yudong Feng, Di Wu, Yankai Xia, Dan Wang, Jinrong Tang, Xianzheng Yuan, Dong Zhu, Jing Wei, Li Xu, Mingkai Xu, Xuetao Guo, Jian Zhao, Qiqing Chen, Zhenming Zhang, Lianzhen Li, Yini Ma, Xiaoxu Jiang, Kai Zhang, Cheng Peng, Mengyao Li, Ning Shen, Willie J. G. M. Peijnenburg, Matthias C. Rillig, Jason C. White, Yongming Luo, Ningwei Zhao   +29 more
wiley   +1 more source

DIAGNOSTIC VALUE OF SPUTUM AND ENDOTRACHEAL ASPIRATE GRAM STAIN

Zdravniški Vestnik, 2002
Background. For decades the microscopic examination of sample Gram stain has been one of the basic diagnostic procedures in the microbiology laboratory. Still opinions about usefulness of sputum and endotracheal aspirate Gram stains in initial management
Viktorija Tomič, Jurij Šorli
doaj  

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source