Results 11 to 20 of about 255,935 (312)

An Innovative Protocol for Metaproteomic Analyses of Microbial Pathogens in Cystic Fibrosis Sputum

Frontiers in Cellular and Infection Microbiology, 2021
Hallmarks of cystic fibrosis (CF) are increased viscosity of mucus and impaired mucociliary clearance within the airways due to mutations of the cystic fibrosis conductance regulator gene.
Alexander C. Graf, Johanna Striesow, Jan Pané-Farré, Thomas Sura, Martina Wurster, Michael Lalk, Dietmar H. Pieper, Dörte Becher, Barbara C. Kahl, Katharina Riedel   +9 more
doaj   +1 more source

The Sputum Microbiome, Airway Inflammation and Mortality in Chronic Obstructive Pulmonary Disease.

Journal of Allergy and Clinical Immunology, 2020
BACKGROUND The sputum microbiome has a potential role in disease phenotyping and risk stratification in chronic obstructive pulmonary disease but few large longitudinal cohort studies exist.
A. Dicker, J. Huang, M. Lonergan, Holly R. Keir, Christopher J. Fong, Brandon Tan, A. Cassidy, S. Finch, H. Mullerova, B. Miller, R. Tal-Singer, J. Chalmers   +11 more
semanticscholar   +1 more source

Common bacteria in sputum or gastric lavage of patients presenting with signs and symptoms of lower respiratory tract infections

The Pan African Medical Journal, 2021
INTRODUCTION: Lower respiratory tract infections (LRTIs) are infections involving the trachea, primary bronchi and lungs. People with LRTIs typically experience coughs as the primary symptoms; however, shortness of breath, weakness, fever and fatigue may
Oliver Deberu, Bernard Nkrumah, Augustina Angelina Sylverken, David Sambian, Godfred Acheampong, John Amuasi, Azure Stebleson, Daron Agboyie, Monica Yenbaree, Sylvester Mensah, Abaifa Dombadoh, Dorcas Ohui Owusu, Abass Abdul-Karim, Michael Owusu   +13 more
doaj   +1 more source

Mapping bacterial diversity and metabolic functionality of the human respiratory tract microbiome

Journal of Oral Microbiology, 2022
Background The Human Respiratory Tract (HRT) is colonized by various microbial taxa, known as HRT microbiota, in a manner that is indicative of mutualistic interaction between such microorganisms and their host.Aim To investigate the microbial ...
Leonardo Mancabelli, Christian Milani, Federico Fontana, Gabriele Andrea Lugli, Chiara Tarracchini, Francesca Turroni, Douwe van Sinderen, Marco Ventura   +7 more
doaj   +1 more source

Comparison of throat swabs and sputum specimens for viral nucleic acid detection in 52 cases of novel coronavirus (SARS-Cov-2)-infected pneumonia (COVID-19)

medRxiv, 2020
Objectives In December 2019, a novel coronavirus (SARS-CoV-2)-infected pneumonia (COVID-19) occurred in Wuhan, China. Laboratory-based diagnostic tests utilized real-time reverse transcriptase polymerase chain reaction (RT-PCR) on throat samples.
Chenyao Lin, J. Xiang, Mingzhe Yan, Hongze Li, Shuang Huang, Changxin Shen   +5 more
semanticscholar   +1 more source

Quick and wide-range taxonomical repertoire establishment of the cystic fibrosis lung microbiota by tandem mass spectrometry on sputum samples

Frontiers in Microbiology, 2022
Microorganisms proteotyping by tandem mass spectrometry has been recently shown as a powerful methodology to identify the wide-range taxonomy and biomass of microbiota.
Pauline Hardouin, Pauline Hardouin, Olivier Pible, Hélène Marchandin, Karen Culotta, Jean Armengaud, Raphaël Chiron, Lucia Grenga   +7 more
doaj   +1 more source

Distinct associations of sputum and oral microbiota with atopic, immunologic, and clinical features in mild asthma.

Journal of Allergy and Clinical Immunology, 2020
Background. Whether microbiome characteristics of induced sputum or oral samples demonstrate unique relationships to features of atopy or mild asthma in adults is unknown. Objective.
J. Durack, Laura S. Christian, S. Nariya, Jeanmarie R. Gonzalez, N. Bhakta, K. M. Ansel, A. Beigelman, M. Castro, A. Dyer, E. Israel, M. Kraft, Richard J. Martin, David T. Mauger, Stephen P. Peters, Sharon R. Rosenberg, C. Sorkness, M. Wechsler, S. Wenzel, S. White, Susan V. Lynch, Homer A. Boushey, Yvonne J Huang   +21 more
semanticscholar   +1 more source

Analysis of sputum in COPD [PDF]

Thorax, 2001
A number of studies have suggested a pathogenetic role for airway inflammation in the induction of both chronic sputum production and chronic airflow obstruction in smokers.1 It is therefore important to characterise and quantify inflammatory changes in the assessment of subjects with chronic obstructive pulmonary disease (COPD).
P. Maestrelli, RICHELDI, Luca, M. Moretti, FABBRI, Leonardo   +3 more
openaire   +7 more sources

Methodological Aspects of Induced Sputum

Advances in Respiratory Medicine, 2023
We aimed to conduct a state-of-the-art review of the current literature and offer further insights into the methodological aspects concerning induced sputum.
Silvano Dragonieri, Andras Bikov, Alessandro Capuano, Simone Scarlata, Giovanna Elisiana Carpagnano   +4 more
doaj   +1 more source

Gram Stain and Culture of Sputum Samples Detect Only Few Pathogens in Community-Acquired Lower Respiratory Tract Infections: Secondary Analysis of a Randomized Controlled Trial

Diagnostics, 2023
Identification of the bacterial etiology of lower respiratory tract infections (LRTI) is crucial to ensure a narrow-spectrum, targeted antibiotic treatment.
Mariana B. Cartuliares, Helene Skjøt-Arkil, Christian B. Mogensen, Thor A. Skovsted, Steen L. Andersen, Andreas K. Pedersen, Flemming S. Rosenvinge   +6 more
doaj   +1 more source