Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Harmonizing the mind and body: The interrelationship between traditional Chinese medicine body constitution, mental health and sleep quality. [PDF]
Yang JJ, Wang Q, Jiang W.
europepmc +1 more source
Ueber die Constitution der Tetrinsäure (α‐Methyl‐tetronsäure) [PDF]
Ludwig Wolff
openalex +1 more source
In Phillips v Director of Public Prosecutions, Witwatersrand Local Division 2003 (1) SACR 425 (CC), the High Court's finding that s 160(d) of the Liquor Act 1989 was unconstitutional came to the Constitutional Court for a confirmation of invalidity. Section 160(d) `made it an offence for any holder of an on-consumption licence who allowed any person (i)
openaire +5 more sources
Politics of the 1945 Constitution:Democratization and Its Impact on Political Institutions in Indonesia [PDF]
Introduction : Before 1998, no one could think about the amendment of the 1945 Constitution. The 1945 Constitution was a product of nationalist who had hard fought for independence from the Dutch colonization.
Kawamura, Koichi
core
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
QI-pathological constitution is associated with mental fatigue in class among university students: a cross-sectional study. [PDF]
Wang X, He X.
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Who is Seeking Traditional Chinese Medicine (TCM) for Cancer? Insights from a Large Cohort in a Rehabilitation Clinic. [PDF]
Zhang Y+9 more
europepmc +1 more source