Results 261 to 270 of about 1,805,078 (297)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The Economics of Constitution-Making [PDF]

, 1982
Watson, William G.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Legal-normative opening by the incorporation of human rights treaties: the contribution of the Inter-American court of human fights for the intended human development in the Constitution of the Federative Republic of Brazil

, 2018
Newton de Menezes Albuquerque, Eduardo Almendra Martins   +1 more
openalex   +1 more source

Constitutional Sedimentation

Legal Issues of Economic Integration, 1996
openaire   +2 more sources

XIX.—On the chemical constitution and artificial formation of taurine

Hermann Kolbe
openalex   +2 more sources

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Constitution Making

2021
Abstract Be it in established democracies or in countries emerging from violent political conflict, constitution-making processes have become a key activity in moments of profound political and social change. Over the last three decades, the field of constitution making has witnessed an explosion of academic research from a variety of
van Lier, F., Seidel, K.
openaire   +2 more sources

Constitutional Economics--Constitutional Politics

Constitutional Political Economy, 1999
Why does the treatment of American constitutional politics presented in We the People depart so radically from models of constitutional deliberation developed in the type of constitutional economics pioneered by James Buchanan and Gordon Tullock? The paper defines three premises that account for the divergence, and concludes by proposing an inquiry ...
openaire   +1 more source

Fiscal Constitutions

Journal of Economic Theory, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
C. AZARIADIS, GALASSO, VINCENZO
openaire   +3 more sources