B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
A comprehensive study of psychological well-being and traditional Chinese medicine constitutions among model workers in Beijing. [PDF]
Cao H+8 more
europepmc +1 more source
Zur Constitution der Phenol‐und Hydrochinon‐Phtaleïnsalze [PDF]
Arthur G. Green, Percy E. King
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
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The correlation between traditional Chinese medicine constitution and primary osteoporosis: A systematic review and meta-analysis. [PDF]
Qu Q+5 more
europepmc +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Clinical characteristics of primary vesicoureteral reflux in children with an allergic constitution. [PDF]
Yin L+5 more
europepmc +1 more source
On the Connection between Chemical Constitution and Physiological Action:—On the Physiological Action of the Salts of Ammonia, of Tri-niethylamine, and of Tetramethyl-ammonium; of the Salts of Tropia, and of the Ammonium Bases derived from it; and of Tropic, Atropic, and Isatropic Acids and their Salts. With further details on the Physiological Action of the Salts of Methyl-Strychnium and of Ethyl-Strychnium [PDF]
A. Crum Brown, Thomas R. Fraser
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