Results 71 to 80 of about 444,140 (312)

Bridging the Heterogeneity of Myasthenia Gravis Scores as a Foundational Step Towards the Construction of a Digital Twin

open access: yesBiomedicines
Background/Objectives: Myasthenia gravis (MG) is a rare autoimmune neuromuscular disease. Clinical trials with rigorously collected data provide valuable opportunities for mathematical modeling of patient outcomes over time.
Marc Garbey   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Constitution Embodiment [PDF]

open access: yes, 2017
In this paper I analyze constitution embodiment, a particular conception of embodiment. Proponents of constitution embodiment claim that the body is a condition of the constitution of entities.
Jeuk, Alexander Albert   +2 more
core   +1 more source

A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders

open access: yesCell Discovery
According to traditional Chinese medicine (TCM) constitutional theory, individuals with phlegm-dampness constitution (PDC) are at increased risk for metabolic disorders. Previous studies have indicated that PDC individuals exhibit gene expression changes
Lingru Li   +19 more
doaj   +1 more source

Successful therapy of Tuomin-Shizhen-decoction in an adult patient with atopic dermatitis-A case report

open access: yesAllergy Medicine
Background: Atopic dermatitis (AD) is an immune-mediated inflammatory skin disease that currently cannot be completely cured. The allergic constitution is the foundation of AD, and the therapy of regulating constitution through Traditional Chinese ...
Yuexuan Gou, Ji Wang, Qi Wang
doaj   +1 more source

Visualizing and measuring gold leaf in fourteenth- and fifteenth-century Italian gold ground paintings using scanning macro X-ray fluorescence spectroscopy: a new tool for advancing art historical research

open access: yesHeritage Science, 2019
The size, shape, and application techniques of gold leaf in fourteenth- and fifteenth-century gold ground panel paintings attributed to artists working in Florence, Siena, and Fabriano was directly visualized using in situ scanning macro X-ray ...
Douglas MacLennan   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Progress report of the Kansas Commission on Constitution Revision [1959]

open access: yes, 1959
Submitted to Hon. George Docking, Governor of the State of Kansas, and the Kansas Legislature.Progress Report of the Kansas Commission on Constitution Revision -- Kansas Commission on Constitution Revision -- Members Appointed By Governor George Docking -
Kansas Commission on Constitution Revision
core  

Sphingolipid metabolites involved in the pathogenesis of atherosclerosis: perspectives on sphingolipids in atherosclerosis

open access: yesCellular & Molecular Biology Letters
Atherosclerosis, with its complex pathogenesis, is a leading underlying cause of many cardiovascular diseases, which are increasingly prevalent in the population. Sphingolipids play an important role in the development of atherosclerosis. Key metabolites
Fufangyu Zhao   +7 more
doaj   +1 more source

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