Results 81 to 90 of about 1,853,445 (346)
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Cellular & Molecular Biology LettersAtherosclerosis, with its complex pathogenesis, is a leading underlying cause of many cardiovascular diseases, which are increasingly prevalent in the population. Sphingolipids play an important role in the development of atherosclerosis. Key metabolites
Fufangyu Zhao +7 more
doaj +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
The Indonesian Constitution 1945: Why was it amended? [PDF]
, 2013 In 1999, 2000, 2001, and 2002, the Indonesian Constitution 1945 was amended by MPR or the People’s Consultative Assembly, the bearer of the people’s sovereignty. The amendment was not without opposition.
Sarsito, Totok
core
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
AI-Powered Telemedicine for Automatic Scoring of Neuromuscular Examinations
BioengineeringTelemedicine is now being used more frequently to evaluate patients with myasthenia gravis (MG). Assessing this condition involves clinical outcome measures, such as the standardized MG-ADL scale or the more complex MG-CE score obtained during clinical ...
Quentin Lesport +4 more
doaj +1 more source
Thinking About the Constitution at the Cusp [PDF]
, 2000 What do I mean in saying that we need to think about the Constitution at the cusp? I have in mind an image in which we have one way of thinking about the Constitution on one side of a line, and another way of thinking about the Constitution on the ...
Tushnet, Mark V.
core +1 more source
Two passages in pseudo-Xenophon [PDF]
, 1995 This paper discusses textual problems in [Xenophon] Athenian Constitution 2.9 and 3 ...
Brock, R., Heath, M.
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Are Foreign Nationals Entitled to the Same Constitutional Rights As Citizens? [PDF]
, 2003 Are foreign nationals entitled only to reduced rights and freedoms? The difficulty of the question is reflected in the deeply ambivalent approach of the Supreme Court, an ambivalence matched only by the alternately xenophobic and xenophilic attitude of ...
Cole, David
core +1 more source