Results 101 to 110 of about 13,641 (276)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
About excitation spectrum of 6He below the energy threshold of decay into t + t [PDF]
Ядерна фізика та енергетика, 2010 Due to measurements and analysis as inclusive proton spectra from the 3Н(a, р) 6Не reaction (Ea = 27.2 MeV) and two-dimensional spectra of p-a coincidences from the four-body 3Н(a,рa)nn reaction (Ea = 27.2 MeV and Ea = 67.2 MeV) was observed the second ...
O. M. Povoroznyk +3 more
doaj
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Discovering novel platinum structures
, 2013 Includes abstract.Includes bibliographical references.The Pt[8]Zr ordering transformation in Pt 11 at. % Zr alloys has been studied. The study included determination of the formation of the Pt[8]Zr phase and its order/disorder transformation temperature (
Mabunda, Khanyisa Prudence
core
Spectra of gamma-rays in (n, xγ) reactions on ferrum and bismuth nuclei [PDF]
Ядерна фізика та енергетика, 2010 The results of the gamma-ray spectra measurements for (n, xγ) reactions induced by 14.1 MeV neutrons on iron and bismuth are presented. Time-of-flight method based on pulse neutron generator was applied.
V. M. Bondar +5 more
doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Applications of artificial neural networks (ANNs) in several different materials research fields
, 2010 PhDIn materials science, the traditional methodological framework is the identification of the composition-processing-structure-property causal pathways that link hierarchical structure to properties.
Zhang, Yiming
core
Intrinsic properties of Hellenic “Marls” [PDF]
, 1993 Post-alpine deposits cover substantial areas of Hellas. The fine grained facies of these deposits, comprise a wide range of over consolidated materials of varying grading and mineralogy.
Tsifoutidis, George
core