Results 131 to 140 of about 13,641 (276)

Transient Things and Permanent Stuff

open access: yes, 2010
A view of individuals as constituted of quantities of matter, both understood as continuants enduring over time, is elaborated in some detail. Constitution is a three-place relation which can't be collapsed to identity because of the place-holder for a ...
Needham, Paul,
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Modelamento matemático do comportamento plástico do sistema argila-água no processo de extrusão [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Fderal de Santa Catarina, Centro Tecnologico, Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Florianópolis, 2009As argilas, quando misturadas com água, adquirem a propriedade chamada plasticidade que
Andrade, Fernando Augusto de
core  

The colouring matter of the flowers of Tagetes patula: Isolation of a new flavonol, patuletin and its constitution

open access: yes, 1941
A new flavonol, patuletin has been isolated from the petals of the flowers of Tagetes patula (French Marigold). It contains five hydroxyl groups and yields a pentaacetate and a pentamethyl ether.
Seshadri, T. R., Suryaprakasa Rao, P.
core   +1 more source

On material and energy sources of formation of fuel-containing materials during Chernobyl NPP UNIT 4 accident

open access: yesЯдерна фізика та енергетика, 2016
Results of detailed analysis of material substance of lava-like fuel-containing materials sources (FCM) and clusters with high uranium concentration were presented.
O. V. Mikhailov
doaj  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

It takes two : defending a two category solution to the problem of material constitution

open access: yes, 2012
Thesis (Ph. D.)--University of Rochester. Dept. of Philosophy, 2009.My dissertation evaluates the merits of a Two Category solution to the problem of material constitution as it arises for artifacts.
Kenny, Patrick Christopher (1974 - )   +1 more
core  

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