Results 91 to 100 of about 107,620 (262)
Chemoenzymatic reactions using the siderophore synthetase DesD from Salinispora tropica and hydroxamic acid substrates (native, non‐native) with different multiplicities (monomer, dimer) and components (homo‐/heterodimer) followed different reaction trajectories, which biased the architectures of the chelator major products and indicated DesD contains ...
Callum A. Rosser +2 more
wiley +1 more source
A Unified Approach for the Synthesis of Conformationally Locked and sp2‐sp3 Fused Hybrids
This study presents a systematic platform to build rigid sp2–sp3 hybrids via benzyne cycloadditions. Arene‑fused bicyclic oxa‐, aza‐, and carbocycles are converted into medicinally relevant amino acids and applied to Enalapril analogues synthesis. The hybrids combine aromatic interactions with 3D rigidity, tuning lipophilicity, pKa, and solubility ...
Ervis Saraci +8 more
wiley +1 more source
Tris(indol‐3‐yl)methanes were synthesized from indoles, CO2, and PhMe2SiH in the presence of BPh3 in acetonitrile at 50°C. One product, tris(4‐bromo‐1‐methylindol‐3‐yl)methane, underwent a palladium‐catalyzed cascade reaction for the formation of a novel polycyclic heteroaromatic compound, where the methine C(sp3) atom originating from CO2 was ...
Sha Li +5 more
wiley +1 more source
ABSTRACT This article argues that China's 2026 Business Mediation Ordinance represents neither progress toward rule of law nor retreat from it. I propose instead that we are witnessing something I call “calibrated autonomy”—the strategic construction of spaces for private ordering that remain tethered to Party‐State oversight through multiple ...
M. Francis Cao
wiley +1 more source
Nitazenes are increasingly present in the illicit drug supply, complicating harm reduction efforts. We have developed a rapid, nontargeted precursor ion scan method to detect emerging nitazenes in real‐world opioid samples. The method identified multiple nitazenes, often replacing pharmaceutical opioids or mixed with fentanyl and benzodiazepines ...
Allie Miskulin +6 more
wiley +1 more source
Toward Comprehensive Climate Action: Assessing Mitigation Approaches Across Canadian Municipalities
ABSTRACT Local governments are widely regarded as key leaders in the global response to climate change. Understanding if and how municipalities commit to climate mitigation is crucial for assessing their contribution to global emission‐reduction goals and identifying barriers to effective climate transitions.
Aryana Soliz +7 more
wiley +1 more source
ABSTRACT Since the 1990s, environmental policy has shifted toward ecosystem protection and biodiversity conservation, a development often described as an ecological turn. This article argues that in practice this turn has taken the form of an ecological “U‐turn,” as environmental ambitions are subordinated to production‐oriented objectives.
Gisle Andersen +2 more
wiley +1 more source
ABSTRACT This study uses the policy regime framework to examine how background conditions, institutions, and actor configurations shaped hunting rights within the forest–wildlife policy domain during Slovenia's postsocialist transformation. Drawing on media analysis, in‐depth interviews with policymakers, and legislative documents, it conducts a ...
Milan Šinko, Brina Malnar
wiley +1 more source
The Hungarian Constitutional Court and Constitutional Identity
Ever since the 2010 parliamentary elections Hungary has set off on the journey to became an ‘illiberal’ member state of the EU, which does not comply with the shared values of rule of law and democracy, the ‘basic structure’ of Europe. The new government of Viktor Orbán from the very beginning has justified the non-compliance by referring to national ...
openaire +3 more sources

