Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair [PDF]
Nucleus, 2019 Constitutive heterochromatin is considered as a functionally inert genome compartment, important for its architecture and stability. How such stable structure is maintained is not well understood.
Vadim O. Chagin +7 more
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RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin [PDF]
eLife, 2017 Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear.
Whitney L Johnson +7 more
doaj +4 more sources
Constitutive Heterochromatin in Eukaryotic Genomes: A Mine of Transposable Elements [PDF]
Cells, 2022 Transposable elements (TEs) are abundant components of constitutive heterochromatin of the most diverse evolutionarily distant organisms. TEs enrichment in constitutive heterochromatin was originally described in the model organism Drosophila ...
René Massimiliano Marsano +1 more
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The Green Valley of Drosophila melanogaster Constitutive Heterochromatin: Protein-Coding Genes Involved in Cell Division Control [PDF]
Cells, 2022 Constitutive heterochromatin represents a significant fraction of eukaryotic genomes (10% in Arabidopsis, 20% in humans, 30% in D. melanogaster, and up to 85% in certain nematodes) and shares similar genetic and molecular properties in animal and plant ...
Giovanni Messina +4 more
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Constitutive heterochromatin controls nuclear mechanics, morphology, and integrity through H3K9me3 mediated chromocenter compaction [PDF]
NucleusAberrant nuclear morphology is a hallmark of human disease and causes nuclear dysfunction. Perturbed nuclear mechanics via reduced heterochromatin weakens the nucleus resulting in nuclear blebbing and rupture.
Gianna Manning +4 more
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Inflammasome, the Constitutive Heterochromatin Machinery, and Replication of an Oncogenic Herpesvirus [PDF]
Viruses, 2021 The success of long-term host–virus partnerships is predicated on the ability of the host to limit the destructive potential of the virus and the virus’s skill in manipulating its host to persist undetected yet replicate efficiently when needed.
Sumita Bhaduri-McIntosh +1 more
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First constitutive heterochromatin characterization and Karyotype of white stork Ciconia ciconia (Aves: Ciconiidae) [PDF]
Brazilian Journal of Biology, 2021 The karyotype and constitutive heterochromatin pattern of the white stork Ciconia ciconia samples obtained from Manzala lake, Dimiaat, Egypt was described. Somatic cells of Ciconia ciconia samples have diploid number 2n= 68 chromosomes.
A. S. M. Abu Shnaf, M. S. Al-Khalifa
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Caryologia, 2021 There is scarce information about the geographical distribution, biological and cytogenetic data from the Rhogeessa hussoni. This study aims to characterize its chromosome composition through chromosome bandings to visualize regions of constitutive ...
Karina Cassia Faria +2 more
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Ring-like distribution of constitutive heterochromatin in bovine senescent cells. [PDF]
PLoS ONE, 2011 BACKGROUND: Cells that reach "Hayflick limit" of proliferation, known as senescent cells, possess a particular type of nuclear architecture. Human senescent cells are characterized by the presence of highly condensed senescent associated heterochromatin ...
Andrey Pichugin +3 more
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Molecular characterization of constitutive heterochromatin in three species of Trypoxylon (Hymenoptera, Crabronidae, Trypoxylini) by CMA3/DAPI staining [PDF]
Comparative Cytogenetics, 2011 Previous cytogenetic analyses in Trypoxylon Latreille, 1796 have been basically restricted to C-banding. In the present study, base-specific CMA3 and DAPI fluorochrome staining were used to characterize the constitutive heterochromatin in three ...
Rodolpho Menezes +3 more
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