Results 101 to 110 of about 25,717 (206)

The distribution pattern of 5-methylcytosine in rye (Secale L.) chromosomes.

open access: yesPLoS ONE, 2020
The rye (Secale L.) genome is large, and it contains many classes of repetitive sequences. Secale species differ in terms of genome size, heterochromatin content, and global methylation level; however, the organization of individual types of sequences in
Anna Kalinka, Magdalena Achrem
doaj   +1 more source

Identification of methotrexate as a heterochromatin-promoting drug. [PDF]

open access: yes, 2019
Heterochromatin is a tightly packed form of DNA involved in gene silencing, chromosome segregation, and protection of genome stability. Heterochromatin is becoming more recognized in tumor suppression and may thus serve as a potential target for cancer ...
Dutta, Pranabananda   +5 more
core   +1 more source

DNA methylation dynamics in aging: How far are we from understanding the mechanisms? [PDF]

open access: yes, 2018
DNA methylation is currently the most promising molecular marker for monitoring aging and predicting life expectancy. However, the mechanisms underlying age-related DNA methylation changes remain mostly undiscovered.Here we discuss the current knowledge ...
Caiafa, Paola   +3 more
core   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei   +9 more
wiley   +1 more source

Satellite DNA sites in four species of the genus Astyanax (Teleostei, Characiformes)

open access: yesGenetics and Molecular Biology, 2007
Cytogenetic data about satellite DNA distribution in four Astyanax species (Characidae) from the Paraitinga river, Paraíba do Sul river basin, Brazil, are presented. In order to characterize the constitutive heterochromatin, C-banding, chromomycin A3 and
Karine Frehner Kavalco   +3 more
doaj   +1 more source

Double in situ hybridization in combination with digital image analysis: A new approach to study interphase chromosome topography [PDF]

open access: yes, 1989
Double in situ hybridization with mercurated and biotinylated chromosome specific DNA probes in combination with digital image analysis provides a new approach to compare the distribution of homologous and nonhomologous chromosome targets within ...
Cremer, Christoph   +9 more
core   +1 more source

Distribution of constitutive heterochromatin in Triatoma melanocephala (Hemiptera, Triatominae)

open access: yesGenetics and Molecular Research, 2014
In principle, Triatoma melanocephala was included in the Brasiliensis subcomplex on the basis of morphological parameters and geographical layout, since there were no other relevant data available in the literature. On the basis of karyotype, it has been proposed to exclude T. melanocephala, as well as of T. vitticeps and T.
Alevi, K. C. C.   +2 more
openaire   +3 more sources

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu   +1 more
wiley   +1 more source

A CRY-BIC negative-feedback circuitry regulating blue light sensitivity of Arabidopsis. [PDF]

open access: yes, 2017
Cryptochromes are blue light receptors that regulate various light responses in plants. Arabidopsis cryptochrome 1 (CRY1) and cryptochrome 2 (CRY2) mediate blue light inhibition of hypocotyl elongation and long-day (LD) promotion of floral initiation. It
Gu, Lianfeng   +15 more
core   +2 more sources

T‐cell exhaustion from a multiomics perspective: Differentiation mechanisms and regulatory networks in the journey from progenitor‐Exhausted T cells to terminally exhausted T cells

open access: yesClinical and Translational Medicine, Volume 16, Issue 2, February 2026.
(1) Core Process: Persistent antigen, from TDLNs to TME, drives Tpex → Tex‐int → Tex‐term differentiation. (2) Multiomics Regulation: This fate transition is orchestrated by a co‐ordinated, multi‐layered molecular network. (3) Functional Outcome: Dysregulated signalling and surging co‐inhibitory receptors lock in proliferative arrest and functional ...
Tong Zhu   +5 more
wiley   +1 more source

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