Results 121 to 130 of about 45,751 (265)

A Solution Set-Based Entropy Principle for Constitutive Modeling in Mechanics [PDF]

, 2018
Entropy principles based on thermodynamic consistency requirements are widely used for constitutive modeling in continuum mechanics, providing physical constraints on a priori unknown constitutive functions. The well-known M\"uller-Liu procedure is based on Liu's lemma for linear systems.
arxiv   +1 more source

Integrated Disease Management, Adaptation and Genomics of Fungal Plant Pathogens in Cropping Systems

Plant Pathology, EarlyView.
Knowledge of the fungal genome and multifaceted evolutionary forces need to be considered together in understanding and managing agricultural plant pathogen adaptation relative to integrated disease management (IDM) strategies. ABSTRACT Crop production systems contribute significantly to maintaining global food security. These systems often involve the
Hayley Wilson, Ido Bar, Kristy Hobson, Niloofar Vaghefi, Toni Petronitis, Rebecca Ford   +5 more
wiley   +1 more source

Candida albicans repetitive elements display epigenetic diversity and plasticity [PDF]

, 2016
Transcriptionally silent heterochromatin is associated with repetitive DNA. It is poorly understood whether and how heterochromatin differs between different organisms and whether its structure can be remodelled in response to environmental signals. Here,
A Ellahi, A Pidoux, A Selmecki, aF Straight, BD Strahl, C Ketel, C Li, C Trapnell, Ca Froyd, CJ Merrick, D Kadosh, DE Gottschling, GD Shankaranarayana, H Chibana, H Chibana, J Haran, J Huang, J Huang, J Nakayama, J Pérez-Martín, J Wendland, JC Tanny, JS Smith, Ka Morano, KR Hansen, L Vasiljeva, LH Freitas-Junior, LN Rusche, M Bryk, M Bühler, M Dubarry, M Paschini, M Van het Hoog, MA Pfaller, MD De Backer, MJ McEachern, N Saksouk, PA Dumesic, PR Lephart, PR Lephart, R Kaur, RB Wilson, RJ Bennett, S Greiss, S Henikoff, S Imai, S Kueng, S Rea, SI Iwaguchi, T Jones, T Kobayashi, T Kobayashi, T Kouzarides, VM Bruno, W Shou, WS Chu, X Bi   +56 more
core   +1 more source

The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation [PDF]

arXiv, 2013
Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are hypertranscribed due to dosage compensation. Here, we dissect the molecular mechanisms and functional pressures driving heterochromatin formation and dosage compensation of the recently formed neo-sex chromosomes ...
arxiv  

Management of T‐cell malignancies: Bench‐to‐bedside targeting of epigenetic biology

CA: A Cancer Journal for Clinicians, EarlyView.
Abstract The peripheral T‐cell lymphomas (PTCL) are the only disease for which four histone deacetylase (HDAC) inhibitors have been approved globally as single agents. Although it is not clear why the PTCL exhibit such a vulnerability to these drugs, understanding the biological basis for this activity is essential.
Ariana Sabzevari, Johnson Ung, Jeffrey W. Craig, Kallesh D. Jayappa, Ipsita Pal, David J. Feith, Thomas P. Loughran Jr, Owen A. O’Connor   +7 more
wiley   +1 more source

Silencing markers are retained on pericentric heterochromatin during murine primordial germ cell development [PDF]

, 2017
Background: In the nuclei of most mammalian cells, pericentric heterochromatin is characterized by DNA methylation, histone modifications such as H3K9me3 and H4K20me3, and specific binding proteins ...
Baarends, W.M. (Willy), Cappellen, W.A. (Gert) van, Eijpe, M. (Maureen), Gribnau, J.H. (Joost), Heijden, G.W. (Godfried) van der, Magaraki, A.M. (Aristea), Magarakis, L. (Leonidas), Peters, A.H.F.M. (Antoine H. F. M.), Sleddens-Linkels, E. (Esther)   +8 more
core   +1 more source

Changes in chromatin state in donors subjected to physical stress [PDF]

arXiv, 2009
The purpose of the present study is to evaluate changes in chromatin of human buccal epithelium under the influence of stressing factor - dosed physical activity. Investigations were performed in a group of students (13 men) of age 19-23. Cells were stained on a slide by a 2% orcein solution in 45% acetic acid during 1 h.
arxiv  

GATA Transcription Factors: A Cross‐Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies

Developmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Alpha‐synuclein (α‐syn), a 140 amino acid protein, is abundantly expressed in the central nervous system (CNS) and in the erythrocytes, playing a pivotal role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies.
Francesco Bellomi, Claudia Caturano, Viola Velardi, Romina Mancinelli, Simone Carotti, Giorgio Vivacqua, Francesca Arciprete, Maria Zingariello   +7 more
wiley   +1 more source

Heterochromatin and the molecular mechanisms of 'parent-of-origin' effects in animals. [PDF]

Twenty five years ago it was proposed that conserved components of constitutive heterochromatin assemble heterochromatinlike complexes in euchromatin and this could provide a general mechanism for regulating heritable (cell-to-cell) changes in gene ...
A Henckel, A Johnson, A Loyola, A Rottach, A Santenard, A Smallwood, A Smallwood, A Thiru, A Yearim, AC Ferguson-Smith, AC Groner, AD Goldberg, AL Nielsen, AT Annunziato, AV Ivanov, B Douarin Le, B Hendrich, B Lehnertz, B Mateescu, B McStay, BM Sirbu, BX Yang, C Alabert, C Baumann, C Dinant, C Francastel, C Goday, C Guetg, C Maison, C Martin, C Muchardt, C Popp, CW Hanna, CW Metz, D Horsley, D Kigami, D Leung, DC Schultz, DC Schultz, DM Messerschmidt, DM Stults, DP Barlow, DTS Pak, E Li, E Matsuda, EB Lewis, EV Chambers, F Cammas, F Dily Le, F Fuks, F Hediger, F Santos, G Buglia, G Kelsey, G Schotta, G Wang, GW Heijden van der, H Epstein, H Guo, H Kobayashi, H Kobayashi, H O'Geen, H Peng, H Sasaki, HPJ Voon, HPJ Voon, HS Chandra, IA Maksakova, IM Krouwels, International Human Genome Sequencing C, J Chen, J Oswald, JA Hackett, JB Spofford, JF Smothers, JR Friedman, JS Becker, K Ayyanathan, K Shirane, K-M Schmitz, KA Wreggett, KE Bachman, KHA Choo, KS Weiler, L Aagaard, L Fritsch, L Schmiedeberg, LH Wei, LH Wong, LM Field, LSH Chuang, M Borkent, M Casanova, M García-Cao, M Guenatri, M Manukyan, M Melcher, M Pannetier, M Schwaiger, M Tardat, M Wossidlo, M-E Torres-Padilla, MA Blasco, MA Surani, MBD Alonso, MC Escribá, MJ Vogel, MJD White, ML Bochman, MS Lechner, N Kourmouli, N Kourmouli, N Murzina, P Drané, P Moosmann, PB Singh, PB Singh, PB Singh, PB Singh, PG Greciano, Prim B Singh, R Amouroux, R Aucott, R Benetti, R Chakrabarti, R Gasser, R Hirasawa, R Jaenisch, R Papait, R Papait, R Paro, R Rebollo, R Riclet, R Santoro, R Schulz, R Sridharan, R Strogantsev, R-S Nozawa, RE Sobel, RF Ryan, RM Marión, RR Meehan, RZ Jurkowska, S Bilodeau, S Bongiorni, S Bongiorni, S Eustermann, S Funaki, S Gonzalo, S Guibert, S Hughes-Schrader, S Iyengar, S Khosla, S Matoba, S Quenneville, S Ratnam, S Seisenberger, S-I Tomizawa, SA Smallwood, SCR Elgin, SF Wolf, SG Prasanth, SH Kwon, SJ Gaunt, SP Rowbotham, SP Sripathy, SW Brown, T Aguirre-Lavin, T Arakawa, T Gagnon-Kugler, T Nakamura, T Zhang, TH Bestor, TL Davis, TS Macfarlan, W Reik, W Rens, WA Nelson‐Rees, WK Baker, WS Saunders, X Li, X Liu, X Zuo, Y Kato, Y Kurihara, Y Liu, Y Obata, Z Anvar, ZD Smith, ZD Smith   +189 more
core   +1 more source

Intrabody-mediated diverting of HP1β to the cytoplasm induces co-aggregation of H3-H4 histones and lamin-B receptor [PDF]

, 2015
Diverting a protein from its intracellular location is a unique property of intrabodies. To interfere with the intracellular traffic of heterochromatin protein 1β (HP1β) in living cells, we have generated a cytoplasmic targeted anti-HP1β intrabody ...
Ainsztein, Akhtar, Alessio Cardinale, Aucott, Bannister, Billur, Biocca, Brown, Bult, Butler, Canzio, Cardinale, Cardinale, Cardinale, Cheutin, Chiti, Cohen, Cowell, Dialynas, Filesi, Filesi, Griffin, Hawkins, Horsley, Ilaria Filesi, Jannot, Jenuwein, Jones, Kirilyuk, Kourmouli, Krebber, Kvam, Lachner, Lavigne, Lechner, Lee, Lener, Lo, Luijsterburg, Mateos-Langerak, Meehan, Minc, Monneret, Muchardt, Nakayama, Nishibuchi, Olins, Olzscha, Orlandi, Ostermeier, Peric-Hupkes, Persic, Poleshko, Polioudaki, Prim B. Singh, Rajpal, Sblattero, Silva, Silvia Biocca, Singh, Smothers, Soria, Taddei, Uversky, Wang, Wreggett, Ye, Ye, Zhang, Zhu   +69 more
core   +1 more source