Results 141 to 150 of about 346,273 (274)

H1N76/77 deamidation facilitates chromatin remodelling and genome stability during DNA damage repair

open access: yesClinical and Translational Medicine, Volume 15, Issue 8, August 2025.
Abstract Chromatin relaxation is a permissiven progress for DNA repair through enabling repair factors to access the damaged DNA. Linker histone H1 is important in maintaining chromatin compaction under physiological state. The recent evidence highlights the importance of H1 modifications in response to cellular stress.
Tingting Feng   +4 more
wiley   +1 more source

Heterochromatin: Guardian of the Genome.

open access: yesAnnual Review of Cell and Developmental Biology, 2018
Constitutive heterochromatin is a major component of the eukaryotic nucleus and is essential for the maintenance of genome stability. Highly concentrated at pericentromeric and telomeric domains, heterochromatin is riddled with repetitive sequences and ...
A. Janssen   +2 more
semanticscholar   +1 more source

AMPK/mTOR/ULK1 Pathway Participates in Autophagy Induction by Curcumin in Colorectal Adenoma Mouse Model

open access: yesDrug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Colorectal adenoma (CRA) represents a pathological condition characterized by the aberrant development of intestinal epithelial cells and alterations in cellular differentiation within the colorectal mucosal epithelium, posing an increased risk for malignant transformation if not adequately addressed. Curcumin has been shown to exhibit a range
Yuge Wang   +4 more
wiley   +1 more source

Comparative cytogenetics in different populations of the cavernicolous diplopod Pseudonannolene strinatii (Diplopoda, Pseudonannolenidae)

open access: yesIheringia: Série Zoologia, 2013
Different populations of Pseudonannolene strinatii Mauriès, 1974 collected from three caves in Iporanga, state of São Paulo, were cytogenetically compared using techniques of conventional coloration, C-banding and silver nitrate impregnation.
Kleber A. Campos, Carmem S. Fontanetti
doaj   +1 more source

Mechanisms governing the accessibility of DNA damage proteins to constitutive heterochromatin. [PDF]

open access: yesFront Genet, 2022
Roemer A   +4 more
europepmc   +1 more source

Sequence-directed curvature of repetitiveAluIDNA in constitutive heterochromatin ofArtemia franciscana [PDF]

open access: bronze, 1989
Roberta Benfante   +3 more
openalex   +1 more source

Interpreting the Origins and Functions of Noncoding RNAs From the Ribosomal Genes

open access: yesJournal of Cellular Physiology, Volume 240, Issue 8, August 2025.
The Ribosomal RNA genes are repressed by the p14/p19ARF tumour suppressor. Activity of an upstream promoter duplication is normally blocked by Transcription Termination Factor 1 (TTF1). However, ARF displaces TTF1, inducing gene repression by “Noncoding‐RNA‐Induced Promoter Occlusion” or RIPO. TTF1 may control other Noncoding RNA generated under stress.
Tom Moss   +2 more
wiley   +1 more source

Location of ribosomal genes in the chromosomes of Anopheles darlingi and Anopheles nuneztovari (Diptera, Culicidae) from the Brazilian Amazon

open access: yesMemorias do Instituto Oswaldo Cruz, 2003
Fluorescence in situ hybridization of Anopheles darlingi and A. nuneztovari demonstrated nucleolar organizer region activity at the end of the fourth larval instar, when the nucleolar organizer regions underwent gradual condensation.
Míriam Silva Rafael   +2 more
doaj   +1 more source

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