Chromosome study in Schistocerca (Orthoptera-Acrididae-Cyrtacanthacridinae): karyotypes and distribution patterns of constitutive heterochromatin and nucleolus organizer regions (NORs). [PDF]
Chromosome analyses were performed in two grasshopper species of the genus Schistocerca, S. pallens and S. flavofasciata. Both species shared the same diploid number (2n = 23, X in males; 2n = 24, XX in females); and a con- served karyotype composed ...
MELO, N. F. de, SOUZA, M. J. de
core
An extra band within the human 9qh+ region that behaves like the surrounding constitutive heterochromatin. [PDF]
José Luís Fernández+4 more
openalex +1 more source
Graphical abstract illustrating the multifaceted approach to harnessing fungal microbiome diversity for antibiotic discovery. Key elements include historical insights, modern genomic tools, and innovative biotechnological strategies for isolating and enhancing fungal antibiotic production.
Md. Sakhawat Hossain+5 more
wiley +1 more source
This review discussed the signaling pathways of Toll‐like receptors in tumors and their antitumor or protumor regulatory effects in diverse tumors. We also paid attention to the application of Toll‐like receptors in clinical treatment and summarized the clinical trial situation in recent years.
Nueraili Maihemuti+7 more
wiley +1 more source
The Antiviral Activity of Polyphenols
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard+5 more
wiley +1 more source
Karyotype, constitutive heterochromatin and nucleolar organizer regions (NORs) in Belosacris coccineipes (Acrididae-Leptysminae) [PDF]
Vilma Loreto, Maria José de Souza
openalex +1 more source
hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan
In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam+15 more
wiley +1 more source
Histone marks enable formation of immiscible phase-separated chromatin compartments
Summary: Eukaryotic chromatin is organized into compartments for gene expression regulation, but the underlying mechanisms remain unclear. Here, we demonstrate that multivalent H3K27me3 and its reader, the CBX7-PRC1 complex, regulate facultative ...
Wenjing Sun+9 more
doaj
Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque
ABSTRACT Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate link between genotype and phenotype, yet genetic effects on DNA methylation remain understudied in natural ...
Christina E. Costa+12 more
wiley +1 more source
Maps of Constitutive-Heterochromatin Distribution for Four Martes Species (Mustelidae, Carnivora, Mammalia) Show the Formative Role of Macrosatellite Repeats in Interspecific Variation of Chromosome Structure. [PDF]
Beklemisheva VR+11 more
europepmc +1 more source