Results 181 to 190 of about 25,717 (206)
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Constitutive heterochromatin in early embryogenesis of Drosophila melanogaster
Molecular and General Genetics MGG, 1991The formation of constitutive heterochromatin was studied during the embryonic development of Drosophila melanogaster, using the C-banding technique. During embryonic cleavage, C-banded material is not seen in mitotic chromosomes; the differentiation between euchromatin and heterochromatin only occurs at blastoderm.
I E, Vlassova +3 more
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Transgenerational epigenetic control of constitutive heterochromatin, transposons, and centromeres
Current Opinion in Genetics & Development, 2023Epigenetic mechanisms are important not only for development but also for genome stability and chromosome dynamics. The latter types of epigenetic controls can often be transgenerational. Here, we review recent progress in two examples of transgenerational epigenetic control: i) the control of constitutive heterochromatin and transposable elements and ...
Tatsuo Fukagawa, Tetsuji Kakutani
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DNase I sensitivity in facultative and constitutive heterochromatin
Chromosoma, 1985In situ nick translation allows the detection of DNase I sensitive and insensitive regions in fixed mammalian mitotic chromosomes. We have determined the difference in DNase I sensitivity between the active and inactive X chromosomes in Microtus agrestis (rodent) cells, along both their euchromatic and constitutive heterochromatic regions. In addition,
K, Sperling +5 more
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Constitutive heterochromatin C-band polymorphism in prostatic cancer
Cancer Genetics and Cytogenetics, 1991The size of the heterochromatin C-bands on chromosomes has been reported to be associated with some, but by no means all, human malignancies. No studies along these lines have been performed in prostatic cancer. We therefore investigated the size, incidence of inversions, and symmetry versus asymmetry of C-band heteromorphisms on chromosomes 1, 9, and ...
R, Lundgren +2 more
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Constitutive heterochromatin propagation contributes to the X chromosome inactivation
Chromosome Research, 2022Imprinted X chromosome inactivation (iXCI) balances the expression of X-linked genes in preimplantation embryos and extraembryonic tissues in rodents. Long noncoding Xist RNA drives iXCI, silencing genes and recruiting Xist-dependent chromatin repressors.
Alexander I. Shevchenko +3 more
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Lateral asymmetry of constitutive heterochromatin in human chromosomes
Human Genetics, 1979Variations in lateral asymmetry of constitutive heterochromatin were studied in 30 normal individuals with reference to the chromosomal regions 1q12, 9q12, 15p11, 16q12 and Yq12. The technique consisted of growing human lymphocytes for one cell cycle in BrdU, staining with 33258 Hoechst, exposing them to UV light, treating them with 2 x SSC, and ...
P K, Ghosh, R, Rani, R, Nand
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Localization of mouse satellite DNA in constitutive heterochromatin
Experimental Cell Research, 1970Abstract Sonication of nuclei from the liver and brain of male mice yields three chromatin fractions with different sedimentation characteristics: a constitutive heterochromatin fraction which sediments at 3500 g, an intermediate chromatin fraction which sediments at 78,000 g and a euchromatin fraction which is recovered by precipitation with ethanol.
W G, Yasmineh, J J, Yunis
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Constitutive heterochromatin: a surprising variety of expressed sequences
Chromosoma, 2009The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult ...
Dimitri P +5 more
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Human Genetics, 1979
Using DAPI staining after pretreatment with distamycin A we detected a familial deficiency of chromosome 16 heterochromatin. A distinct positively staining band, however, was seen after C-banding. Thus, by using these different heterochromatin staining methods, heterogeneity of the constitutive heterochromatin in the centromeric region of human ...
Buys, C.H.C.M. +4 more
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Using DAPI staining after pretreatment with distamycin A we detected a familial deficiency of chromosome 16 heterochromatin. A distinct positively staining band, however, was seen after C-banding. Thus, by using these different heterochromatin staining methods, heterogeneity of the constitutive heterochromatin in the centromeric region of human ...
Buys, C.H.C.M. +4 more
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Asynchronous replication of constitutive heterochromatin on X chromosomes in female Mus dunni
Chromosoma, 1982Euchromatin DNA of one X chromosome in mammalian females, which becomes facultatively heterochromatinized, is known to replicate asynchronously late in S phase compared to its active homologue. In the females of a pygmy mouse species Mus dunni, which has prominent segment of constitutive heterochromatin as the short arm of its submetacentric X ...
S, Sen, T, Sharma
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