Polymeric nature of tandemly repeated genes enhances assembly of constitutive heterochromatin in fission yeast. [PDF]
Yamamoto T, Asanuma T, Murakami Y.
europepmc +3 more sources
A constitutive heterochromatic region shapes genome organization and impacts gene expression in Neurospora crassa [PDF]
Background Organization of the eukaryotic genome is essential for proper function, including gene expression. In metazoans, chromatin loops and Topologically Associated Domains (TADs) organize genes into transcription factories, while chromosomes occupy ...
Andrew T. Reckard+5 more
doaj +2 more sources
PhpCNF-Y transcription factor infiltrates heterochromatin to generate cryptic intron-containing transcripts crucial for small RNA production [PDF]
The assembly of repressive heterochromatin in eukaryotic genomes is crucial for silencing lineage-inappropriate genes and repetitive DNA elements. Paradoxically, transcription of repetitive elements within constitutive heterochromatin domains is required
Manjit Kumar Srivastav+10 more
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Molecular characterization of constitutive heterochromatin in three species of Trypoxylon (Hymenoptera, Crabronidae, Trypoxylini) by CMA3/DAPI staining [PDF]
Previous cytogenetic analyses in Trypoxylon Latreille, 1796 have been basically restricted to C-banding. In the present study, base-specific CMA3 and DAPI fluorochrome staining were used to characterize the constitutive heterochromatin in three ...
Rodolpho Menezes+3 more
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H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation [PDF]
Background Heterochromatin is a fundamental component of eukaryotic chromosome architecture, crucial for genome stability and cell type-specific gene regulation.
Kei Fukuda+2 more
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Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks. [PDF]
Heinz KS+6 more
europepmc +3 more sources
Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression. [PDF]
Chavan A+12 more
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Constitutive heterochromatin formation and transcription in mammals. [PDF]
Constitutive heterochromatin, mainly formed at the gene-poor regions of pericentromeres, is believed to ensure a condensed and transcriptionally inert chromatin conformation. Pericentromeres consist of repetitive tandem satellite repeats and are crucial chromosomal elements that are responsible for accurate chromosome segregation in mitosis. The repeat
Saksouk N, Simboeck E, Déjardin J.
europepmc +5 more sources
Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin. [PDF]
Jamieson K+7 more
europepmc +3 more sources
Constitutive heterochromatin distribution in pig (Sus scrofa) chromosomes [PDF]
Constitutive heterochromatin (HC = C-banding) distribution was studied in pig (Sus5crofa) chromosomes from 20 animals belonging to Cinta Senese and Calabrese breeds raised in southern Italy. The use of CBG-banding, sequential GBG/CBA-banding and sequential GBG/ Ag-NOR/CBA-banding techniques allowed more detailed characterization of C-banding patterns ...
G.P. Di Meo+5 more
openalex +8 more sources