Constitutive heterochromatin formation and transcription in mammals. [PDF]
Epigenetics Chromatin, 2015 Constitutive heterochromatin, mainly formed at the gene-poor regions of pericentromeres, is believed to ensure a condensed and transcriptionally inert chromatin conformation. Pericentromeres consist of repetitive tandem satellite repeats and are crucial chromosomal elements that are responsible for accurate chromosome segregation in mitosis. The repeat
Saksouk N, Simboeck E, Déjardin J.
europepmc +5 more sources
Stress-induced activation of heterochromatic transcription. [PDF]
PLoS Genetics, 2010 Constitutive heterochromatin comprising the centromeric and telomeric parts of chromosomes includes DNA marked by high levels of methylation associated with histones modified by repressive marks.
Mireille Tittel-Elmer +5 more
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Suv39h1 links the SUMO pathway to constitutive heterochromatin. [PDF]
Mol Cell Oncol, 2016 The Suv39h lysine methyltransferases, known as key enzymes responsible for histone H3 lysine 9 methylation, are critical for heterochromatin protein 1 enrichment at constitutive heterochromatin. Our recent findings reveal a new role for the Suv39h1 paralog that links it to SUMO pathway function at constitutive heterochromatin.
Maison C, Quivy JP, Almouzni G.
europepmc +4 more sources
CHROMOSOMIC STUDIES IN ZEPHYRANTHES CITRINA BAKER (AMARYLLIDACEAE), A POLYPLOID ORNAMENTAL [PDF]
BAG. Journal of Basic and Applied Genetics, 2022 Zephyranthes citrina is an ornamental American bulbous plant used as an ornamental garden crop for the aesthetic qualities of its yellow perigonium.
Daviña J.R. +5 more
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The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken [PDF]
, 2005 The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals.
Bonifer, C. +8 more
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On the evolution of Yeti, a Drosophila melanogaster heterochromatin gene. [PDF]
PLoS ONE, 2014 Constitutive heterochromatin is a ubiquitous and still unveiled component of eukaryotic genomes, within which it comprises large portions. Although constitutive heterochromatin is generally considered to be transcriptionally silent, it contains a ...
Roberta Moschetti +4 more
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The analysis of pendolino (peo) mutants reveals differences in the fusigenic potential among Drosophila telomeres [PDF]
, 2015 Drosophila telomeres are sequence-independent structures that are maintained by transposition to chromosome ends of three specialized retroelements (HeT-A, TART and TAHRE; collectively designated as HTT) rather than telomerase activity. Fly telomeres are
Burla, Romina +8 more
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Constitutive heterochromatin reorganization during somatic cell reprogramming [PDF]
The EMBO Journal, 2011 Induced pluripotent stem (iPS) cell reprogramming is a gradual epigenetic process that reactivates the pluripotent transcriptional network by erasing and establishing repressive epigenetic marks. In contrast to loci-specific epigenetic changes, heterochromatin domains undergo epigenetic resetting during the reprogramming process, but the effect on the ...
Fussner, Eden +8 more
openaire +3 more sources
Chromosome mapping of dragline silk genes in the genomes of widow spiders (araneae, theridiidae) [PDF]
, 2010 With its incredible strength and toughness, spider dragline silk is widely lauded for its impressive material properties. Dragline silk is composed of two structural proteins, MaSp1 and MaSp2, which are encoded by members of the spidroin gene family ...
Ayoub, NA, Hayashi, CY, Zhao, Y
core +7 more sources
On the relations of phase separation and Hi-C maps to epigenetics [PDF]
Royal Society Open Science, 2020 The relationship between compartmentalization of the genome and epigenetics is long and hoary. In 1928, Heitz defined heterochromatin as the largest differentiated chromatin compartment in eukaryotic nuclei.
Prim B. Singh, Andrew G. Newman
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