A constitutive heterochromatic region shapes genome organization and impacts gene expression in Neurospora crassa. [PDF]
BMC GenomicsBackground Organization of the eukaryotic genome is essential for proper function, including gene expression. In metazoans, chromatin loops and Topologically Associated Domains (TADs) organize genes into transcription factories, while chromosomes occupy ...
Reckard AT +5 more
europepmc +2 more sources
Journal of reproduction and development, 2012 Phosphorylation of histone H3 at Ser10 (H3S10P) has been linked to a variety of cellular processes, such as chromosome condensation and gene activation/silencing.
Karlla Ribeiro-Mason +7 more
semanticscholar +3 more sources
PhpCNF-Y transcription factor infiltrates heterochromatin to generate cryptic intron-containing transcripts crucial for small RNA production. [PDF]
Nat CommunThe assembly of repressive heterochromatin in eukaryotic genomes is crucial for silencing lineage-inappropriate genes and repetitive DNA elements. Paradoxically, transcription of repetitive elements within constitutive heterochromatin domains is required
Srivastav MK +10 more
europepmc +2 more sources
Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term [PDF]
BMC Developmental Biology, 2009 BackgroundGenome reprogramming in early mouse embryos is associated with nuclear reorganization and particular features such as the peculiar distribution of centromeric and pericentric heterochromatin during the first developmental stage.
W. Maalouf +6 more
semanticscholar +2 more sources
New Cytogenetic Data for the Neottieae Tribe (Orchidaceae) in the Mediterranean Region. [PDF]
Plants (Basel)This work presents a summary of cytogenetic data, including new information, on several species within the tribe Neottieae, with an update of the karyotype for 23 species belonging to the genera Cephalanthera, Limodorum, Epipactis, and Neottia (including
Turco A +4 more
europepmc +2 more sources
Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression. [PDF]
PLoS BiolChavan A +12 more
europepmc +2 more sources
From Effective Interactions Extracted Using Hi-C Data to Chromosome Structures in Conventional and Inverted Nuclei [PDF]
PRX Life 1, 013010 (2023), 2023 Contact probabilities between loci, separated by arbitrary genomic distance, for a number of cell types have been reported using genome-wide chromosome conformation capture (Hi-C) experiments. How to extract the effective interaction energies between active euchromatin (A) and inactive heterochromatin (B) directly from the experimental data, without an
arxiv +1 more source
CHROMOSOMIC STUDIES IN ZEPHYRANTHES CITRINA BAKER (AMARYLLIDACEAE), A POLYPLOID ORNAMENTAL [PDF]
BAG. Journal of Basic and Applied Genetics, 2022 Zephyranthes citrina is an ornamental American bulbous plant used as an ornamental garden crop for the aesthetic qualities of its yellow perigonium.
Daviña J.R. +5 more
doaj +1 more source
Stress-induced activation of heterochromatic transcription. [PDF]
PLoS Genetics, 2010 Constitutive heterochromatin comprising the centromeric and telomeric parts of chromosomes includes DNA marked by high levels of methylation associated with histones modified by repressive marks.
Mireille Tittel-Elmer +5 more
doaj +1 more source
Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023 FA is a progressive neurodegenerative disorder, but the primary cause of death is heart disease which occurs in 60% of the patients. Several functions of frataxin have been proposed, but none of them fully explain why its deficiency causes the FA phenotypes nor why the most affected cell types are neurons and cardiomyocytes.
Mariana B. Angulo +6 more
wiley +1 more source