Results 21 to 30 of about 12,566 (212)
Constitutive heterochromatin formation and transcription in mammals. [PDF]
Epigenetics Chromatin, 2015 Constitutive heterochromatin, mainly formed at the gene-poor regions of pericentromeres, is believed to ensure a condensed and transcriptionally inert chromatin conformation. Pericentromeres consist of repetitive tandem satellite repeats and are crucial chromosomal elements that are responsible for accurate chromosome segregation in mitosis. The repeat
Saksouk N, Simboeck E, Déjardin J.
europepmc +5 more sources
Constitutive heterochromatin studies in patients with solid tumors
Journal of Cancer Research and Clinical Oncology, 1986 Constitutive heterochromatin of chromosomes 1, 9, and 16 was studied in 101 patients with solid tumors and 85 controls. Lymphocyte cultures were used for performing C-banded chromosome preparations. Two homologous chromosomes were regarded as heteromorphic when there was a 25% difference between their C-band size or when they fell into different ...
Stefan Suciu
openalex +4 more sources
Sequence-dependent heterochromatin formation in the human malaria parasite Plasmodium falciparum
Heliyon, 2023 The human malaria parasite Plasmodium falciparum represses transcription of the gene encoding AP2-G, which is the master regulator of germ cell differentiation, via heterochromatin condensation following histone H3 lysine 9 trimethylation (H3K9me3 ...
Toshiyuki Mori, Mai Nakashima
doaj +1 more source
CHROMOSOMIC STUDIES IN ZEPHYRANTHES CITRINA BAKER (AMARYLLIDACEAE), A POLYPLOID ORNAMENTAL [PDF]
BAG. Journal of Basic and Applied Genetics, 2022 Zephyranthes citrina is an ornamental American bulbous plant used as an ornamental garden crop for the aesthetic qualities of its yellow perigonium.
Daviña J.R. +5 more
doaj +1 more source
Stress-induced activation of heterochromatic transcription. [PDF]
PLoS Genetics, 2010 Constitutive heterochromatin comprising the centromeric and telomeric parts of chromosomes includes DNA marked by high levels of methylation associated with histones modified by repressive marks.
Mireille Tittel-Elmer +5 more
doaj +1 more source
On the evolution of Yeti, a Drosophila melanogaster heterochromatin gene. [PDF]
PLoS ONE, 2014 Constitutive heterochromatin is a ubiquitous and still unveiled component of eukaryotic genomes, within which it comprises large portions. Although constitutive heterochromatin is generally considered to be transcriptionally silent, it contains a ...
Roberta Moschetti +4 more
doaj +1 more source
On the relations of phase separation and Hi-C maps to epigenetics [PDF]
Royal Society Open Science, 2020 The relationship between compartmentalization of the genome and epigenetics is long and hoary. In 1928, Heitz defined heterochromatin as the largest differentiated chromatin compartment in eukaryotic nuclei.
Prim B. Singh, Andrew G. Newman
doaj +1 more source
Imaging the Response to DNA Damage in Heterochromatin Domains
Frontiers in Cell and Developmental Biology, 2022 The eukaryotic genome is assembled in a nucleoprotein complex called chromatin, whose organization markedly influences the repair of DNA lesions. For instance, compact chromatin states, broadly categorized as heterochromatin, present a challenging ...
Audrey Chansard +3 more
doaj +1 more source
PLoS Genetics, 2022 Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing.
R A Greenstein +5 more
doaj +1 more source
The Proteomic Composition and Organization of Constitutive Heterochromatin in Mouse Tissues. [PDF]
CellsPericentric heterochromatin (PCH) forms spatio-temporarily distinct compartments and affects chromosome organization and stability. Albeit some of its components are known, an elucidation of its proteome and how it differs between tissues in vivo is lacking.
Schmidt A +10 more
europepmc +6 more sources