Results 31 to 40 of about 353,053 (207)
On the evolution of Yeti, a Drosophila melanogaster heterochromatin gene. [PDF]
PLoS ONE, 2014 Constitutive heterochromatin is a ubiquitous and still unveiled component of eukaryotic genomes, within which it comprises large portions. Although constitutive heterochromatin is generally considered to be transcriptionally silent, it contains a ...
Roberta Moschetti +4 more
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On the relations of phase separation and Hi-C maps to epigenetics [PDF]
Royal Society Open Science, 2020 The relationship between compartmentalization of the genome and epigenetics is long and hoary. In 1928, Heitz defined heterochromatin as the largest differentiated chromatin compartment in eukaryotic nuclei.
Prim B. Singh, Andrew G. Newman
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Biology of the Cell, Volume 115, Issue 1, January 2023., 2023 We review here recent studies reporting the importance of both nuclear lamina components and epigenetic modifications of chromatin in nuclear mechanics. Perturbation of chromatin condensation or nuclear lamina has been linked to a plethora of biological conditions whose most studied examples are accelerated Hutchinson‐Gilford Progeria Syndrome (HGPS ...
Pietro Salvatore Carollo, Viviana Barra
wiley +1 more source
Brain Pathology, Volume 33, Issue 1, January 2023., 2023 Schematic depicting characterization of pathological tau signatures and nuclear alterations in neurons, astrocytes and microglia in neurodegenerative diseases. Abstract Accumulation of pathological tau aggregates is a prominent feature in tauopathies that leads during the course of the diseases to neuronal dysfunction before and cell death after ...
Mauro Montalbano +4 more
wiley +1 more source
PLoS Genetics, 2022 Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing.
R A Greenstein +5 more
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Imaging the Response to DNA Damage in Heterochromatin Domains
Frontiers in Cell and Developmental Biology, 2022 The eukaryotic genome is assembled in a nucleoprotein complex called chromatin, whose organization markedly influences the repair of DNA lesions. For instance, compact chromatin states, broadly categorized as heterochromatin, present a challenging ...
Audrey Chansard +3 more
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Histone variants shape chromatin states in Arabidopsis
eLife, 2023 How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone ...
Bhagyshree Jamge +8 more
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Iheringia: Série Zoologia, 2002 Using conventional staining with acetic orcein and C-banding techniques it was investigated constitutive heterochromatin chromosomal polymorphisms and the mitotic and the meiotic behavior of male and female chromosomes of Boophilus microplus (Canestrini,
Rosane Nunes Garcia +3 more
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MeCP2 dependent heterochromatin reorganization during neural differentiation of a novel Mecp2-deficient embryonic stem cell reporter line. [PDF]
PLoS ONE, 2012 The X-linked Mecp2 is a known interpreter of epigenetic information and mutated in Rett syndrome, a complex neurological disease. MeCP2 recruits HDAC complexes to chromatin thereby modulating gene expression and, importantly regulates higher order ...
Bianca Bertulat +10 more
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Brazilian Journal of Biology, 2021 The karyotype and constitutive heterochromatin pattern of the white stork Ciconia ciconia samples obtained from Manzala lake, Dimiaat, Egypt was described. Somatic cells of Ciconia ciconia samples have diploid number 2n= 68 chromosomes.
A. S. M. Abu Shnaf, M. S. Al-Khalifa
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