Imaging the Response to DNA Damage in Heterochromatin Domains
Frontiers in Cell and Developmental Biology, 2022 The eukaryotic genome is assembled in a nucleoprotein complex called chromatin, whose organization markedly influences the repair of DNA lesions. For instance, compact chromatin states, broadly categorized as heterochromatin, present a challenging ...
Audrey Chansard +3 more
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SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae [PDF]
, 2011 Budding yeast centromeres are sequence-defined point centromeres and are, unlike in many other organisms, not embedded in heterochromatin. Here we show that Fun30, a poorly understood SWI/SNF-like chromatin remodeling factor conserved in humans ...
Anna T. Vetter +13 more
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PLoS Genetics, 2022 Heterochromatin spreading, the expansion of repressive chromatin structure from sequence-specific nucleation sites, is critical for stable gene silencing.
R A Greenstein +5 more
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Constitutive heterochromatin polymorphism in river buffalo chromosomes [PDF]
Caryologia, 1995 Constitutive heterochromatin (HC) distribution among river buffalo (Bubalus bubalis L., 2n=50) chromosomes was analyzed by using both the CBA-technique and GBA + CBA technique. CBA-banding revealed the presence of HC in the centromeric regions of all the chromosomes of the 15 animals we investigated.
DI MEO GP +4 more
openaire +3 more sources
Histone variants shape chromatin states in Arabidopsis
eLife, 2023 How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone ...
Bhagyshree Jamge +8 more
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ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing. [PDF]
, 2009 Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications, including DNA methylation, histone H3 dimethylation at Lys9 (H3K9me2) and monomethylation at Lys27 (H3K27me1).
Bernatavichute, Yana V +9 more
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Qualitative analysis of constitutive heterochromatin and primate evolution [PDF]
Biological Journal of the Linnean Society, 2003 The results of qualitative heterochromatin analysis in 16 species of primates: Homo sapiens, Pan troglodytes and Gorilla gorilla (F. Hominidae), Hylobates syndactilus (F. Hylobatidae), Macaca fascicularis, M. tibetana, Mandrillus sphinx, M. leucophaeus, Cercopithecus aethiops, C. sabaeus and C. albogularis (F.
F. García +5 more
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Accessibility of promoter DNA is not the primary determinant of chromatin-mediated gene regulation [PDF]
, 2019 DNA accessibility is thought to be of major importance in regulating gene expression. We test this hypothesis using a restriction enzyme as a probe of chromatin structure and as a proxy for transcription factors.
Chereji, Razvan V. +4 more
core +1 more source
Transcription of satellite DNAs in insects [PDF]
, 2011 Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic +3 more
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Pre-implantation mouse embryos cultured In vitro under different oxygen concentrations show altered ultrastructures [PDF]
, 2020 Assisted Reproductive Technologies routinely utilize different culture media and oxygen (O2) concentrations to culture human embryos. Overall, embryos cultured under physiological O2 tension (5%) have improved development compared to embryos cultured ...
Antonouli, S +6 more
core +1 more source