Results 121 to 130 of about 1,763,243 (270)
ANALYSIS OF EXCAVATION-INDUCED DEFORMATION WITH DIFFERENT SOIL MODELS
TASK Quarterly, 2010 The monitored case of deep excavation works located in the centre of Warsaw is described and back analysed as a boundary value problem with the finite element method. The excavation was carried out in over-consolidated clayey layers under the support of
MARCIN CUDNY, PAWEŁ POPIELSKI
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
MicromachinesOwing to potential inaccuracies in the current stress–strain curve used for constructing the Johnson–Cook (JC) constitutive model of amorphous alloys, the parameters of the JC constitutive equation were derived using Oxley’s cutting theory, negative ...
Jinguang Du +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
A Constitutive Modelling Outlook on Arterial (dys)function: Bridging the Gap with the Clinic
Artery ResearchThe compliant properties of arteries are pivotal to cardiovascular function and arise from the concerted work of a highly specialised wall microstructure comprising compliant elastin, progressively recruited, stiff collagen fibres, and contractile ...
A. Giudici
doaj +1 more source
Microstructure Simulation and Constitutive Modelling of Magnetorheological Fluids Based on the Hexagonal Close-packed Structure. [PDF]
Materials (Basel), 2020 Zhang J +6 more
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source