Results 41 to 50 of about 332,949 (253)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Constrained Application Protocol Profile for Robust Header Compression Framework

, 2021
Due to the extensive growth of Internet of Things (IoT), the number of wireless devices connected to the Internet is increasing and will continue to increase remarkably in the near future. In wireless networks, the available bandwidth is always restricted.
Majanen Mikko, Koskela Pekka
openaire   +2 more sources

Resource Allocation in Wireless Networks with RF Energy Harvesting and Transfer [PDF]

, 2014
Radio frequency (RF) energy harvesting and transfer techniques have recently become alternative methods to power the next generation of wireless networks. As this emerging technology enables proactive replenishment of wireless devices, it is advantageous
Han, Zhu, Lu, Xiao, Niyato, Dusit, Wang, Ping   +3 more
core   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Security for the Industrial IoT: The Case for Information-Centric Networking

, 2018
Industrial production plants traditionally include sensors for monitoring or documenting processes, and actuators for enabling corrective actions in cases of misconfigurations, failures, or dangerous events.
Frey, Michael, Gündoğan, Cenk, Kietzmann, Peter, Lenders, Martine, Petersen, Hauke, Schmidt, Thomas C., Shzu-Juraschek, Felix, Wählisch, Matthias   +7 more
core   +1 more source

Building self-optimized communication systems based on applicative cross-layer information [PDF]

, 2008
This article proposes the Implicit Packet Meta Header(IPMH) as a standard method to compute and represent common QoS properties of the Application Data Units (ADU) of multimedia streams using legacy and proprietary streams’ headers (e.g.
Chassot, Christophe, Dairaine, Laurent, Exposito, Ernesto, Gineste, Mathieu   +3 more
core   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Application Protocols enabling Internet of Remote Things via Random Access Satellite Channels

, 2017
Nowadays, Machine-to-Machine (M2M) and Internet of Things (IoT) traffic rate is increasing at a fast pace. The use of satellites is expected to play a large role in delivering such a traffic. In this work, we investigate the use of two of the most common
Bacco, Manlio, Colucci, Marco, Gotta, Alberto   +2 more
core   +1 more source

Fuzzy based load and energy aware multipath routing for mobile ad hoc networks [PDF]

, 2015
Routing is a challenging task in Mobile Ad hoc Networks (MANET) due to their dynamic topology and lack of central administration. As a consequence of un-predictable topology changes of such networks, routing protocols employed need to accurately capture ...
Ali, M., Shahrabi, A., Stewart, B.G., Vallavaraj, A.   +3 more
core   +3 more sources