Results 51 to 60 of about 335,875 (298)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Unified clustering and communication protocol for wireless sensor networks [PDF]
In this paper we present an energy-efficient cross layer protocol for providing application specific reservations in wireless senor networks called the “Unified Clustering and Communication Protocol ” (UCCP). Our modular cross layered framework satisfies
Aslam, Nauman +2 more
core +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
During the last decade, the number of devices capable of connecting to the Internet has grown enormously. The Internet of Things describes a scenario where Internet connected devices are ubiquitous and even the smallest device has a connection to the ...
Höglund, Rikard
core +1 more source
An ANT+ Protocol Based Health Care System [PDF]
In remote health care Body Area Networks (BAN) are very popular but demand low energy consumption due to very constrained resources. For it several protocols, such as ZigBee, BlueTooth, WiFi etc, have been proposed but non has delivered the optimum ...
CULMONE, Rosario, MEHMOOD, NADEEM QAISAR
core +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
A Sleep-Awake Scheme Based on CoAP for Energy-Efficiency in Internet of Things
Internet Engineering Task Force (IETF) have developed Constrained Application Protocol (CoAP) to enable communication between sensor or actuator nodes in constrained environments, such as small amount of memory, and low power. IETF CoAP and HTTP are used
Wenquan Jin, DoHyeun Kim
doaj +1 more source
Enhancing Block-Wise Transfer with Network Coding in CoAP
CoAP (Constrained Application Protocol) with block-wise transfer (BWT) option is a known protocol choice for large data transfer in general lossy IoT network environments.
Dizdarevic, Jasenka +2 more
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source

