Results 111 to 120 of about 2,345,368 (345)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Constrained minimization of smooth functions using a genetic algorithm [PDF]

open access: yes, 1994
The use of genetic algorithms for minimization of differentiable functions that are subject to differentiable constraints is considered. A technique is demonstrated for converting the solution of the necessary conditions for a constrained minimum into an
Moerder, Daniel D., Pamadi, Bandu N.
core   +1 more source

A Penalized Subspace Strategy for Solving Large-Scale Constrained Optimization Problems [PDF]

open access: yes, 2021
International audienceMany data science problems can be efficiently addressed by minimizing a cost function subject to various constraints. In this paper a new method for solving largescale constrained differentiable optimization problems is proposed. To
Martin, Ségolène   +2 more
core  

Lagrange multipliers estimates for constrained minimization [PDF]

open access: yes, 1981
We discuss in this work the first-order, second-order and pseudo-second-order estimations of Lagrange multipliers in nonlinear constrained minimization.
Escudero, L. F.   +1 more
core   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

An experimental comparison of min-cut/max- flow algorithms for energy minimization in vision [PDF]

open access: yes, 2004
Minimum cut/maximum flow algorithms on graphs have emerged as an increasingly useful tool for exactor approximate energy minimization in low-level vision.
Yuri Boykov   +3 more
core  

WP6 Performance assessment – Uncertainty evaluation Interlaboratory Comparisons on CRM1 [PDF]

open access: yes, 2021
International audienceThe characterization of site or installation to be dismantled is a crucial step in the process: it is essential to define the actions to be carried out. The INSIDER (Improved Nuclear SIte characterization for waste minimization in D&
Crozet, Marielle   +2 more
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Large-scale security constrained optimal reactive power flow for operational loss management on the GB electricity transmission network [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Engineering Doctorate and awarded by Brunel University, 22/12/2010.The transmission of power across the GB transmission system, as operated by National Grid, results in inevitable loss of electrical power ...
Macfie, Peter
core  

Inexact Bregman iteration with an application to Poisson data reconstruction [PDF]

open access: yes, 2013
This work deals with the solution of image restoration problems by an iterative regularization method based on the Bregman iteration. Any iteration of this scheme requires to exactly compute the minimizer of a function.
Ruggiero, V   +3 more
core   +1 more source

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