Results 101 to 110 of about 2,345,368 (345)
Optimality conditions for interval-valued univex programming
Journal of Inequalities and Applications, 2019 We introduce concepts of interval-valued univex mappings, consider optimization conditions for interval-valued univex functions for the constrained interval-valued minimization problem, and show examples for the illustration purposes.
Lifeng Li, Jianke Zhang, Chang Zhou
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Continuous dependence of solutions for indefinite semilinear elliptic problems
Electronic Journal of Differential Equations, 2013 We consider the superlinear elliptic problem $$ -\Delta u + m(x)u = a(x)u^p $$ in a bounded smooth domain under Neumann boundary conditions, where $m \in L^{\sigma}(\Omega)$, $\sigma\geq N/2$ and $a\in C(\overline{\Omega})$ is a sign changing ...
Elves A. B. Silva, Maxwell L. Silva
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Relaxed Viscosity Approximation Methods with Regularization for Constrained Minimization Problems
Journal of Applied Mathematics, 2013 We introduce a new relaxed viscosity approximation method with regularization and prove the strong convergence of the method to a common fixed point of finitely many nonexpansive mappings and a strict pseudocontraction that also solves a convex ...
Lu-Chuan Ceng +2 more
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Constrained Minimization Under Vector-Valued Criteria in Linear Topological Spaces [PDF]
, 1967 Constrained minimization under vector valued criteria in linear topological ...
Polak, E., Da Cunha, N. O.
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A New Nonconvex Sparse Recovery Method for Compressive Sensing
Frontiers in Applied Mathematics and Statistics, 2019 As an extension of the widely used ℓr-minimization with 0 < r ≤ 1, a new non-convex weighted ℓr − ℓ1 minimization method is proposed for compressive sensing.
Zhiyong Zhou, Jun Yu
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FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Modified sequential unconstrained minimization technique methods for constrained optimization. [PDF]
, 1994 Modified sequential unconstrained minimization technique methods for constrained ...
Lixing. Jia (7984664)
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