Results 101 to 110 of about 860,607 (233)

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

open access: yesAdvanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka   +10 more
wiley   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

open access: yesAdvanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri   +3 more
wiley   +1 more source

Higher order spherical harmonics reconstruction of fetal diffusion MRI with intensity correction

open access: yes, 2018
We present a comprehensive method for reconstruction of fetal diffusion MRI signal using a higher order spherical harmonics representation, that includes motion, distortion and intensity correction.
Georgia Lockwood Estrin   +11 more
core   +1 more source

Raman Analysis of RNA Nucleotide Strands From SARS‐CoV‐2 Variants and Subvariants: A Step Forward in the Definition of “Raman Genome”

open access: yesAdvanced Science, EarlyView.
Main Raman signals in RNA, related to helical backbone, ribofuranose ring, and nitrogenous bases, are affected by secondary structures that cause hyperchromic effects and significantly alter the Raman intensity. ABSTRACT Raman spectra of RNA nucleotide strands extracted from 20 SARS‐CoV‐2 strains, including the original Japanese isolate, Alpha, Beta ...
Giuseppe Pezzotti   +11 more
wiley   +1 more source

A pitfall in the reconstruction of fibre ODFs using spherical deconvolution of diffusion MRI data

open access: yes
Diffusion weighted (DW) MRI facilitates non-invasive quantification of tissue microstructure and, in combination with appropriate signal processing, three-dimensional estimates of fibrous orientation.
Marshall, Andrew David   +5 more
core   +2 more sources

Blind deconvolution of sparse pulse sequences under a minimum distance constraint: a partially collapsed Gibbs sampler method [PDF]

open access: yes, 2012
For blind deconvolution of an unknown sparse sequence convolved with an unknown pulse, a powerful Bayesian method employs the Gibbs sampler in combination with a Bernoulli–Gaussian prior modeling sparsity.
Kail, Georg   +3 more
core   +1 more source

Synthetic Shewanella‐Bacillus Microbial Consortia for Enhanced Metal Oxide Leaching From Spent Lithium‐Ion Batteries Using Brewing Wastewater as Leaching Agent

open access: yesAdvanced Science, EarlyView.
A recycling approach of spent lithium‐ion batteries is developed using brewing wastewater as the leaching agent and an engineering microbial consortium as the biocatalyst. Shewanella oneidensis reduces spent LiNixCoyMn1‐x‐yO2 cathodes via extracellular electron transfer, while Bacillus subtilis removes residual ethanol to eliminate inhibition.
Baocai Zhang   +14 more
wiley   +1 more source

Limbic-motor areas interactions as revealed by Constrained Spherical Deconvolution tractography: a mechanism to shape complex motor behaviors?

open access: yes, 2016
Although there are several evidence in animal research on the emotional motor-limbic subcortical system including amygdala, hyppocampus, parahyppocampal cortex and nucleus accumbens, little is know about its connection to cortical motor-related areas.....
TRIMARCHI, Fabio   +7 more
core  

Electron‐Beam Enables Spatially Resolved Defect‐Mediated Work Function Modulation in FAPbI3 Perovskite Thin Films

open access: yesAdvanced Science, EarlyView.
Electron‐beam irradiation enables defect‐mediated work function modulation in metal halide perovskites by regulating interstitial iodides. This approach allows continuous Fermi‐level tuning and spatially resolved formation of lateral surface‐potential‐defined junctions with built‐in potential.
Hyeonho Park   +9 more
wiley   +1 more source

Dipy, a library for the analysis of diffusion MRI data

open access: yesFrontiers in Neuroinformatics, 2014
Diffusion Imaging in Python (Dipy) is a free and open source software projectfor the analysis of data from diffusion magnetic resonance imaging (dMRI)experiments. dMRI is an application of MRI that can be used to measurestructural features of brain white
Eleftherios eGaryfallidis   +7 more
doaj   +1 more source

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