Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Additive Manufacturing in Organic Chemistry: From Synthesis to Sustainable Process Design. [PDF]
Domiński A +2 more
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ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega +4 more
wiley +1 more source
Physics-Informed Side-Scan Sonar Perception: Tackling Weak Targets and Sparse Debris via Geometric and Frequency Decoupling. [PDF]
Yu B, Lin R, Zhou H, Zhang J, Zhang X.
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A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter +5 more
wiley +1 more source
Design of a Novel, Modular, Mouth Retractor: A Concept Testing Study. [PDF]
Aljibe MSO, Apacible AMC, Fullante PB.
europepmc +1 more source
A G-Code-Driven Modeling and Thermo-Mechanical Coupling Analysis Method for the FDM Process of Complex Lightweight Structures. [PDF]
Li D, Dun Y, Yang Z, Zhou R, Chen Y.
europepmc +1 more source
Neuro-Geometric Graph Transformers with Differentiable Radiographic Geometry for Spinal X-Ray Image Analysis. [PDF]
Kaveevorayan V +5 more
europepmc +1 more source
Energy-efficient path planning for Robotic Bulkhead Inspection using Residual-Enhanced UKF and Hierarchical MPC. [PDF]
Wang J, Li L, Gao R, Yang L.
europepmc +1 more source
Molecular simulation-based 3D structural construction of olfactory receptor with agonist binding. [PDF]
Hirao T +5 more
europepmc +1 more source

