Results 41 to 50 of about 1,803,631 (274)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A backward analysis for constraint logic programs [PDF]

open access: yesTheory and Practice of Logic Programming, 2002
One recurring problem in program development is that of understanding how to re-use code developed by a third party. In the context of (constraint) logic programming, part of this problem reduces to figuring out how to query a program. If the logic program does not come with any documentation, then the programmer is forced to either experiment with
Andy King, Lunjin Lu
openaire   +4 more sources

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Exploiting Fashion Features for Floor Storage Systems in the Shoe Industry

open access: yesInternational Journal of Engineering Business Management, 2013
Floor storage systems are used in the shoe industry to store fashion products of seasonal collections of low quantity and high variety. Since space is valuable and order picking must be sped up, stacking of shoeboxes should be optimized.
Antonella Meneghetti
doaj   +1 more source

Dicast: um sistema inteligente para auxílio ao projeto de peças fundidas Dicast: an intelligent system to assist the design of casting parts

open access: yesGestão & Produção, 1997
Este artigo aborda a questão da integração das atividades de projeto e manufatura, descrevendo um sistema de engenharia desenvolvido para auxiliar os projetistas na etapa de projeto detalhado de peças fundidas. O projetar é considerado como uma atividade
Ricardo M. Naveiro, Peter O'Grady
doaj   +1 more source

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi   +4 more
wiley   +1 more source

CONSTRAINT PROGRAMMING AND UNIVERSITY TIMETABLING

open access: yesSouth African Journal of Industrial Engineering, 2012
<p>ENGLISH ABSTRACT: The technology of Constraint Programming is rapidly becoming a popular alternative for solving large-scale industry problems.
G.W. Groves, W. Van Wijck
doaj  

Simplified Algorithmic Metatheorems Beyond MSO: Treewidth and Neighborhood Diversity [PDF]

open access: yesLogical Methods in Computer Science, 2019
This paper settles the computational complexity of model checking of several extensions of the monadic second order (MSO) logic on two classes of graphs: graphs of bounded treewidth and graphs of bounded neighborhood diversity.
Dušan Knop   +3 more
doaj   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

open access: yesAdvanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed   +6 more
wiley   +1 more source

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