Results 91 to 100 of about 495,604 (291)

Priority-Driven Dynamic Constraint Boundary Relaxation: A Framework for Multi-Constraint Conflict Resolution

IEEE Access
This paper presents a priority-based dynamic constraint boundary relaxation (PDCBR) framework for managing multi-constraint conflicts. In the first stage, a two-dimensional model incorporating rigidity and impact intensity sets the constraint ...
Yang Liu
doaj   +1 more source

A Practical Optimality Condition Without Constraint

, 1999
A new optimality condition for minimization with general constraints is introduced. Unlike the KKT conditions, this condition is satisfied by local minimizers of nonlinear programming problems, independently of constraint qualifications.
Qualifications For Nonlinear, Benar Fux Svaiter   +1 more
core  

Constraint qualifications in linear vector semi-infinite optimization

, 2013
Linear vector semi-infinite optimization deals with the simultaneous minimization of finitely many linear scalar functions subject to infinitely many linear constraints.
Goberna, Miguel A., Guerra Vázquez, Francisco, Todorov, Maxim I.   +2 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Nonsmooth KKT-type optimality and duality for multiobjective fractional bilevel optimization via tangential subdifferentials

Results in Applied Mathematics
This paper studies a class of nondifferentiable multiobjective fractional bilevel optimization problems. Under suitable nonsmooth constraint qualifications, necessary optimality conditions of the Karush– Kuhn–Tucker (KKT) type are established using ...
Rishabh Pandey, Savin Treanţă, Yogendra Pandey, Vinay Singh   +3 more
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Hybrid qualifications - Increasing the value of vocational education and training in the context of lifelong learning

, 2010
The initial major task of the EU Leonardo project ‘Hybrid Qualifications increasing the value of Vocational Education and Training in the context of Lifelong Learning’ has been to develop individual country reports.
Davey, Gayna, Fuller, Alison
core   +1 more source

Observations of constraint qualifications for quasiconvex programming

In this paper, we introduce duality theorems and their constraint qualifications for quasiconvex programming.
Suzuki, Satoshi
core  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source