Results 141 to 150 of about 13,147 (249)

Disparate Mechanical and Functional Properties of Spontaneously Hypertensive Rat and Spontaneously Hypertensive Heart Failure Rat Penetrating Arterioles. [PDF]

J Cardiovasc Pharmacol
Acosta C, Anderson HD, Anderson CM.
europepmc   +1 more source

144: Pathologic vascular response in fetal-placental arteries constricted with thromboxane after exposure to maternal hyperglycemia in a human dual perfusion placenta model [PDF]

American Journal of Obstetrics and Gynecology, 2016
Luckey C. Reed, Nicholas Leronimakis, Peter G. Napolitano   +2 more
openaire   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

Advanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu, Haozhe Ren, Hua Li, Jinghan Zhao, Miaomiao Cao, Tian Tang, Youbei Qiao, Liting Chen, Tiehong Yang, Hong Wu   +9 more
wiley   +1 more source

Male Circumcision Revisited: A Narrative Review of Techniques, Therapeutic Indications, and Preventive Benefits. [PDF]

Cureus
Hasan MR, Hossain A, Sakib N.
europepmc   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu, Haojie Chen, Xiang Li, Jingxin Liu, Yiwen Li, Zhenyi Shi, Shenshen Guo, Qingfeng Du, Aiping Lu, Daogang Guan   +9 more
wiley   +1 more source

The use of ultrasound guidance for endometrial sampling in patient populations with known or suspected cervical stenosis: A retrospective case review. [PDF]

Gynecol Oncol Rep
Nail C, Moufarrij S, Mueller JJ, Leitao MM, Abu-Rustum NR, Chi DS, Li D.   +6 more
europepmc   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Preoperative Ultrasound Correctly Localized Peripheral Nerve Abnormalities for Operative Guidance: A Retrospective Review. [PDF]

HSS J
Cha N, Zusstone E, Ko L, Lee SK, J Milani C, Feinberg JH, Wolfe SW, Nwawka OK.   +7 more
europepmc   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source

Right posterior communicating artery aneurysm with multiple arterial stenoses and moyamoya disease: A case report. [PDF]

J Int Med Res
Liu J, Shi Z, Liu H, Wen G.
europepmc   +1 more source