The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Uniting Physics and Perception: How Constructal Law Governs Human Categorization
This work establishes a fundamental connection between Constructal Law and human cognition, proposing that categorization evolved to maximize behavioral freedom through optimal information flow.
Robert Contofalsky
core +6 more sources
A Review of Constructal Design of Heat Exchangers
A substantial amount of research has been dedicated to improving the efficiency of heat exchangers, which are extensively utilized in electronic equipment, heating and air conditioning systems, space vehicles, thermal power systems, industrial ...
Salemaa Rashid Salih +2 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Constructal Law and Thermoeconomic Optimization
The paper introduces the concept of Thermoeconomic Environment and discusses how the Constructal Theory can be applied to the productive structure of an energy system.
CASISI M., REINI M.
core +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
A Constructal law perspective of cancer’s volume/area expansion ratio
Constructal law is used to improve the analysis of the resonant heat transfer in cancer cells. The result highlights the fundamental role of the volume/area ratio and of its role in cancer growth and invasion.
Grisolia, G. +3 more
core
Geometric optimization of complex thermal-fluid dynamic system by means of constructal design [PDF]
In this work the Constructal Theory is exposed in its generality, trying to approach it through examples mostly of a physical-engineering nature. Constructal Theory proposes to see living bodies as elements subject to constraints, which are built with a ...
Impiombato, Andrea Natale <1990>
core +1 more source
Architecture After Irreversibility
Architecture has often represented itself through permanence, stability, and formal autonomy while materially existing through irreversible exchanges, dissipation, aging, maintenance, and transformation.
Lazaros Mavromatidis
doaj +1 more source
Dendritic design as an archetype for growth patterns in Nature: fractal and constructal views
The occurrence of configuration (design, shape, structure, rhythm) is a universal phenomenon that occurs in every flow system. Dendritic configuration (or tree-shaped configurations) is ubiquitous in nature and likely to arise in both animate and ...
Antonio F. Miguel
doaj +1 more source

