Results 41 to 50 of about 5,631,563 (275)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Constructal Law and the Unifying Principle of Design
, 2013 Design happens everywhere, whether in animate objects (e.g., dendritic lung structures, bacterial colonies, and corals), inanimate patterns (river basins, beach slope, and dendritic crystals), social dynamics (pedestrian traffic flows), or engineered ...
Rocha, Luiz A. O. +3 more
core +1 more source
Applied Sciences, 2020 This numerical study aims to investigate the influence of I and T-shaped empty channels’ geometry on the filling time of resin in a rectangular porous enclosed mold, mimicking the main operating principle of a liquid resin infusion (LRI) process ...
Glauciléia M. C. Magalhães +7 more
doaj +1 more source
Reserves, Injury Severity, and Outcomes in Traumatic Brain Injury: A CENTER‐TBI Observational Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Reserve refers to the brain's ability to maintain function after an injury and strongly relates to traumatic brain injury (TBI) outcomes. This study examined (1) whether associations between pre‐injury reserve proxies and outcomes differed across injury severity categories, and (2) whether the impact of injury severity varied across ...
Natascha Ekdahl +6 more
wiley +1 more source
SHAPES AND HEAT TRANSFER IN CANCER: THE CONSTRUCTAL RESONANCE [PDF]
, 2019 Any cell process requires energy, so a control of the energy conversion in the cell can represent a way to control the cell processes. Cells regulate their metabolisms by fluxes of energy and mass (ions included). The Constructal law is the thermodynamic
Grisolia G., Lucia U.
core
Constructal Law: Optimization as Design Evolution
, 2015 Copyright © 2015 by ASME. Here, I review the physics meaning of optimization, knowledge and design evolution, and why these concepts and human activities are profoundly useful for human life.
Bejan, A
core +1 more source
Arthritis Care &Research, EarlyView.Objective Ambulatory care–sensitive conditions (ACSCs) serve as indicators of access, quality, and performance of the health system. This study aimed to determine rheumatoid arthritis (RA)‐specific ACSCs for use in the evaluation of care system access and quality.
Kara Irwin +7 more
wiley +1 more source
Constructal design of T-shaped cavity cooled by convection
, 2011 In this paper, we rely on the Constructal method to optimize the geometry of a T-shaped cavity intruded into a conducting solid wall. The cavity is cooled by a steady stream of convection while the solid generates heat uniformly and it is insulated on ...
Dos Santos E. D. +10 more
core +1 more source
Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch
International Journal of Adaptive Control and Signal Processing, EarlyView.This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane +3 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt +8 more
wiley +1 more source