Results 91 to 100 of about 3,507,125 (317)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Minor rotor tines and knives soil interaction. Total power calculation for minor rotor drive
Introduction. The problem of fast and high-quality road construction, when economic facilities and settlements are spatially separated, located at a considerable distance from each other, cannot be solved without the use of a complex of continuous units.
V. A. Nikolaiev
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
School storm shelter study report : to the 133rd Ohio General Assembly
"December 2019."; Includes bibliographical referencesIntroduction -- Consultation with stakeholders -- Building code requirements for school storm shelters -- Storm shelter cost impact on OFCC projects -- 2018 moratorium -- 2019 moratorium and study ...
Ohio Facilities Construction Commission
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Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Thermal Behaviour Assessment of Brick Utilizing Plastic Waste for Enhanced Insulation Properties
Plastic waste, particularly hazardous types such as high-density polyethylene (HDPE) and Polyethylene terephthalate (PTE), is a critical problem in today’s world.
Nuranis Yasira +4 more
doaj
The relevance of the research topic is manifested in the fact that the strengthening of the Russian identity of the residents of Donbass is taking place in the context of an information war with Ukrainian nationalism.
A. V. Baranov, Yu. V. Kostenko
doaj +1 more source
Mapping the e-business profile and trends in cost management in the UK construction industry
The advancement of e-business applications and IT infrastructure has had massive impact on construction business processes over the last decade. The added effects of globalisation coupled with global economic recession have forced businesses to implement
Zhou, Lei +5 more
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Safety effectiveness indicators (SEI's): measuring construction industry safety performance [PDF]
The current application of Positive Perfromance Indicators (PPI's) in the construction industry largely measures numbers of disparate safety activities. Generally they are seen by industry as not providing generalizable indicators of safety effectiveness
Biggs, Herbert C. +4 more
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