Results 81 to 90 of about 3,507,125 (317)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
International Journal of Occupational and Environment Safety, 2018 The need to improve the safety management in the maintenance and operational works on a motorway is a request that all the organizations demand to achieve better goals on safety and in the use of resources. The use of instruments linked to efficiency and
José Eduardo Silva, Carlos Rodrigues
doaj +1 more source
Exit Statement : 2001-2009 CRC for Construction Innovation
, 2009 The Cooperative Research Centre (CRC) for Construction Innovation is Australia’s national centre for research and innovation focused on the needs of the property, design, construction and facility management sectors. The period covered by this report is
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Mathematical models of multi-barreled construction artillery systems
Structural Mechanics of Engineering Constructions and Buildings, 2018 The article presents the schematic diagrams and mathematical models of multi-barrel artillery systems designed for shooting and extraction of building elements from the ground, describes the results of numerical experiments carried out on the basis of ...
Oleg L Figovsky, Oleg G Pensky
doaj +1 more source
, 2009 This document provides an overview of the differences and similarities in the objectives and implementation frameworks of the training and employment policies applying to public construction projects in Western Australia and Queensland.
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The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Construction process categorisation towards developing an E-business maturity model
, 2014 The rapid pace of change in technology coupled with global economic and environmental changes has had considerable impact on all business sectors. Consequently, organisations are forced to drive towards efficiency savings, productivity improvements and ...
Zhou, Lei +4 more
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