Results 81 to 90 of about 4,844,251 (306)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Project Performance Evaluation of Multi-prime Contracts in Comparison with General Contractor Contracts

open access: yesJournal of Asian Architecture and Building Engineering, 2017
This research focuses on multi-prime (MP) contracts, as an alternative contracting method to general contractor (GC) contracts, to reduce the construction costs of the Korean government.
Kyungrai Kim
doaj   +1 more source

Identification of ex-ante and ex-post transaction costs in industrial construction engineering projects

open access: yesJournal of Civil Engineering and Management, 2018
Construction costs comprise not only production but also transaction costs, which can be categorized as ex-ante (pre-contractual) and ex-post (post-contractual) costs.
Fábio Bellotti da Fonseca   +2 more
doaj   +1 more source

The Secular and Cyclic Behavior of "True" Construction Costs [PDF]

open access: yes
Current construction cost indices typically are derived by applying national weights to local costs for materials and labor. In this study, construction cost indices are developed that are based on actual contractor tenders for projects.
William C. Wheaton   +1 more
core  

Construction process categorisation towards developing an E-business maturity model [PDF]

open access: yes, 2014
The rapid pace of change in technology coupled with global economic and environmental changes has had considerable impact on all business sectors. Consequently, organisations are forced to drive towards efficiency savings, productivity improvements and ...
Zhou, Lei   +4 more
core  

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Construction project budgeting including time buffers and costs

open access: yesBudownictwo i Architektura, 2014
The proposed method presented in this article concerns cost estimating of projects, including contingency. It points to the possibility of application of time buffers for this purpose.
Mieczysław Połoński
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Report : enabling team collaboration with pervasive and mobile computing : cost benefit analysis methodology [PDF]

open access: yes, 2006
Construction is an information intensive industry in which the accuracy and\ud timeliness of information is paramount. It observed that the main\ud communication issue in construction is to provide a method to exchange\ud data between the site operation,

core  

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