Results 61 to 70 of about 4,844,251 (306)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Determinants of transaction costs in construction projects

open access: yesJournal of Civil Engineering and Management, 2015
Transaction costs occur when a good or service is transferred across a technologically separable interface, and include the costs of drafting, negotiating and enforcing an agreement, and also the costs of governance and bonding to secure commitments.
Huimin Li, David Arditi, Zhuofu Wang
doaj   +1 more source

Final report : task 4 : waste minimisation in construction [PDF]

open access: yes, 2005
The Regenerating Construction Project for the CRC for Construction Innovation aims to\ud assist in the delivery of demonstrably superior ‘green’ buildings.

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Factors influencing transaction costs in construction projects : a critical review

open access: yes, 2016
The management of large-scale construction projects involves the efficient and effective management of financial resources. The physical cost of a construction project governs the estimation of construction budgets and forecasts.
Zhang, Guomin   +7 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Exit Statement : 2001-2009 CRC for Construction Innovation [PDF]

open access: yes, 2009
The Cooperative Research Centre (CRC) for Construction Innovation is Australia’s national centre for research and innovation focused on the needs of the property, design, construction and facility management sectors. The period covered by this report is

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Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A machine-learning model for estimating construction renovation costs

open access: yes
Purpose A serious concern for construction costs has been the presence of uncertainties in construction operations and how they affect project performance. Several models exist for predicting construction project costs.
Muhammad Aliyu Yamusa   +6 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

A framework for assessing social policy inclusion proposals [PDF]

open access: yes, 2009
This document outlines a framework that could be used by government agencies in assessing policy interventions aimed at achieving social outcomes from government construction contracts.

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