Results 41 to 50 of about 180,075 (262)

Construction costs of tunnel form buildings

Građevinar, 2013
A residential building with a lateral load resisting system, adopted as a reference example, is considered in the paper. The system is made of shear walls realized using the tunnel form technology. The building is modelled for a varying number of floors,
Zeynep Yeşim İlerisoy, Mehmet Emin Tuna   +1 more
doaj   +1 more source

COST ANALYSIS IN CONSTRUCTION OF UNDERGROUND MINING STRUCTURES AND OPPORTUNITIES FOR THEIR REDUCTION

Rudarsko-geološko-naftni Zbornik, 2015
The construction of underground mining facilities is of essential importance to the exploitation of mineral resources. Confirmation of this is the fact that the construction costs of main facilities occupy 40-60% of the underlying investments in the main
Nikolinka Doneva, Zoran Despodov, Dejan Mirakovski, Marija Hadzi-Nikolova, Stojanče Mijalkovski   +4 more
doaj   +1 more source

ANALYSIS OF THE EFFECT OF INDIRECT COSTS ON THE PERFORMANCE OF CONSTRUCTION PROJECT IMPLEMENTATION

Jurnal Pensil, 2023
The success of a construction project performance can be seen from the timeliness of completion of the implementation of work that has been agreed upon by the owner and contractor.
Ihsan
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Principii de bază privind metodologia costurilor pe ciclul de viaţă al construcţiilor la nivel european [PDF]

Urbanism. Arhitectura. Constructii, 2011
Making life-cycle cost methodology is an acknowledgment of the need for Europe-wide methodology for life cycle buildings costs. The aim of this study is to provide a methodological framework for the universal application of lifetime costs in the ...
Silviu Lambrache
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Determinants of transaction costs in construction projects

Journal of Civil Engineering and Management, 2015
Transaction costs occur when a good or service is transferred across a technologically separable interface, and include the costs of drafting, negotiating and enforcing an agreement, and also the costs of governance and bonding to secure commitments.
Huimin Li, David Arditi, Zhuofu Wang
doaj   +1 more source