Results 41 to 50 of about 247,555 (312)

COST ANALYSIS IN CONSTRUCTION OF UNDERGROUND MINING STRUCTURES AND OPPORTUNITIES FOR THEIR REDUCTION

Rudarsko-geološko-naftni Zbornik, 2015
The construction of underground mining facilities is of essential importance to the exploitation of mineral resources. Confirmation of this is the fact that the construction costs of main facilities occupy 40-60% of the underlying investments in the main
Nikolinka Doneva, Zoran Despodov, Dejan Mirakovski, Marija Hadzi-Nikolova, Stojanče Mijalkovski   +4 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Toplu Konut Projelerinde Maliyetlerin Regresyon Metodu ile İncelenmesi

Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2014
Bu çalışmada Türkiye Cumhuriyeti Başbakanlık Toplu Konut İdaresi Başkanlığı (TOKİ)’nin yapımını gerçekleştirdiği toplu konut projelerinde kattaki daire sayıları, kat adetleri, yapı blok sayısı, toplam alan (m2), yapım yılı maliyetleri, yapım yılı ve 2013
Ali Rıza Sivri, Latif Onur Uğur
doaj   +2 more sources

Flowchart Design for Checking of Supplier’s Financial Claims

Civil and Environmental Engineering
This article deals with the topic of financial claims within a construction project. The aim of the article is to create a flowchart for the supplier’s financial requirements, which could serve as an aid for the participating entities in the framework of
Strělcová Iveta, Černovický Vojtěch
doaj   +1 more source

Construction costs of tunnel form buildings

Građevinar, 2013
A residential building with a lateral load resisting system, adopted as a reference example, is considered in the paper. The system is made of shear walls realized using the tunnel form technology. The building is modelled for a varying number of floors,
Zeynep Yeşim İlerisoy, Mehmet Emin Tuna   +1 more
doaj   +1 more source

ANALYSIS OF THE EFFECT OF INDIRECT COSTS ON THE PERFORMANCE OF CONSTRUCTION PROJECT IMPLEMENTATION

Jurnal Pensil, 2023
The success of a construction project performance can be seen from the timeliness of completion of the implementation of work that has been agreed upon by the owner and contractor.
Ihsan
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source