Results 71 to 80 of about 11,523,814 (287)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

A Shared Ontology for Logistics Information Management in the Construction Industry

open access: yes, 2020
Logistics management plays an essential role in supporting the primary activities in manufacturing industries. Similarly, in the construction industry, logistics operations are a crucial part that directly influence the construction operations ...
Antti Peltokorpi   +9 more
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Low-carbon indoor humidity regulation via 3D-printed superhygroscopic building components

open access: yesNature Communications
Indoor humidity can significantly impact our comfort and well-being, often leading to the use of mechanical systems for its management. However, these systems can result in substantial carbon emissions and energy precarity.
Magda Posani   +7 more
doaj   +1 more source

Optimizing Ventilation Inlet and Outlet Configurations using a UQ-Informed Robotic Sensing Platform [PDF]

open access: yesE3S Web of Conferences
It is of paramount importance to provide Indoor Air Quality (IAQ) as it can improve health, productivity, and well-being of the users while reducing the energy consumption.
Xiao Yi   +5 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Estimating the Influence of Improper Workplace Environment on Human Error: Posterior Predictive Analysis

open access: yesAdvances in Civil Engineering, 2018
A model for identifying, analyzing, and quantifying the mechanisms for the influence of improper workplace environment on human error in elevator installation is proposed in this study.
Pin-Chao Liao   +4 more
doaj   +1 more source

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