FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Understanding Occupational and Skill Demand in New Jersey's Construction Industry [PDF]
, 2005 The construction industry is integral to New Jersey's economy, employing over 160,000 people. Nationally and in New Jersey, the construction industry is thriving, injecting billions of dollars into the state.
Denise Pierson-Balik +6 more
core
Application of fine-grained binding materials in technology of hardening backfill construction [PDF]
, 2014 The expediency of differential formation of high filling massif chambers based on a developed technology with usage of fine-grained binding materials.
Kuzmenko, O, Petlyovanyy, M
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Air-Entraining Effect on Rheological Properties of Cement-Based Mixtures
Advances in Materials Science and EngineeringThe rheological properties and stability of cement-based materials determine the technological properties of concrete mixtures and significantly influence concrete properties.
Aigerim Tolegenova +3 more
doaj +1 more source
Simplified Life Cycle Analysis. A Rural School in La Pampa, Argentina [PDF]
, 2014 This study case is a rural school in La Pampa, Argentina, where we compare two energy efficiency systems for construction: the local traditional building type and a proposed one, based on passive system design during its life cycle.
Czajkowski, Jorge Daniel +1 more
core +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Determination of the airborne sound insulation of a straw bale partition wall [PDF]
, 2017 This paper describes the results of a scientific project focused on determining of the Airborne Sound Insulation of a peripheral non-load bearing wall made of straw bales expressed by Weighted Sound Reduction Index.
Fabian, Radek +2 more
core +1 more source
Efficient construction of linear models in materials modeling and applications to force constant expansions [PDF]
, 2020 Linear models, such as force constant (FC) and cluster expansions, play a key role in physics and materials science. While they can in principle be parametrized using regression and feature selection approaches, the convergence behavior of these ...
Erhart, Paul +2 more
core +2 more sources