Results 81 to 90 of about 8,806,849 (303)

Numerical Evaluation Method of Hydraulic Circuits Including Devices That Stabilise Pressure

open access: yesThe Journal of Engineering
This study develops a numerical algorithm for unsteady fluid flow for short and long hydraulic systems, including various hydraulic devices in the system, through scientific searches for new ways to protect long pipeline systems from sudden pressure ...
Paschal Chimeremeze Chiadighikaobi   +7 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Construction materials and their processing

open access: yes
The special issue contains articles that are dedicated to the analysis of the latest research results in the area of structural and functional materials and their processing and synthesis technologies, including methods of their applications in machinery

core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Spontaneous hierarchical surface engineering of minerals through coupled dissolution‐precipitation chemistry

open access: yesAggregate
Peculiar hierarchical microstructures in creatures inspire modern material design with distinct functionalities. Creatures can effortlessly construct sophisticated yet long‐range ordered microstructure across bio‐membrane through ion secretion and ...
Jinyang Jiang   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Molecular pathways governing the earliest stages of C–S–H nucleation [PDF]

open access: yesMaterials Advances
Understanding how calcium silicate hydrate (C–S–H) cluster emerge from dissolved species remains a central challenge in cement science, as experimental probes cannot fully resolve the earliest atomistic events.
K. M. Salah Uddin   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Identifying Nano-Enabled Construction Materials [PDF]

open access: yes
Nanomaterials are very small. They are many times thinner than a human hair. Materials that contain engineered nanomaterials are called nano-enabled. Engineered nanomaterials are mostly used in paints, coatings, and sealants.

core  

Optimal Design of Reinforced Concrete Materials in Construction

open access: yes, 2022
The structural design process is iterative and involves many design parameters. Thus, this paper presents a controlled framework for selecting the adequate structural floor system for reinforced concrete buildings and efficiently utilizing the ...
Salah El-Din Fahmy Taher   +2 more
core   +1 more source

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