Results 81 to 90 of about 3,082,738 (358)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Numerical Evaluation Method of Hydraulic Circuits Including Devices That Stabilise Pressure

open access: yesThe Journal of Engineering
This study develops a numerical algorithm for unsteady fluid flow for short and long hydraulic systems, including various hydraulic devices in the system, through scientific searches for new ways to protect long pipeline systems from sudden pressure ...
Paschal Chimeremeze Chiadighikaobi   +7 more
doaj   +1 more source

CONSTRUCTION ENGINEERING AND CONSTRUCTION MATERIALS

open access: yesEPRA International Journal of Multidisciplinary Research (IJMR), 2019
Construction Engineering is very important part of Civil Engineering. We can’t think about a good and stable structure without good quality of construction. And the construction materials is also play an important role for any construction work. Construction engineering is a professional discipline that deals with the designing, planning, construction ...
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Use of Strain-Hardening Cement-Based Composites (SHCC) for Retrofitting

open access: yesMATEC Web of Conferences, 2018
Strain-hardening cement-based composites (SHCC, or Engineered Cementitious Composites, ECC) were developed in the early 1990th and have been since then an object of numerous investigations which number increases every year.
Müller Steffen, Mechtcherine Viktor
doaj   +1 more source

Design and Construction of Device for Rubber Material Fatigue Test

open access: diamond, 2021
Saddam K. Al-Raheem   +2 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Some durability aspects of hybrid alkaline cements

open access: yesMATEC Web of Conferences, 2014
Blended cements that contain a high content of fly ash and a low content of Portland cement typically suffer from low early strength development and long setting times. Recently, one method of overcoming these problems has been to use an alkali activator
Donatello S.   +3 more
doaj   +1 more source

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