Results 91 to 100 of about 26,640,468 (347)

Housing supply chain model for innovation: research report [PDF]

, 2011
The aim of this research is to undertake a case study analysis of successful delivery of an innovation to the Australian housing construction industry.
Jessica Siva, Kerry London
core  

Dynamic walking with Dribbel [PDF]

, 2006
This paper describes the design and construction of Dribbel, a passivity-based walking robot. Dribbel has been designed and built at the Control Engineering group of the University of Twente. This paper focuses on the practical side: the design approach,
Dertien, Edwin
core   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Digital Twin Success Factors and Their Impact on Efficiency, Energy, and Cost Under Economic Strength: A Structural Equation Modeling and XGBoost Approach

Buildings
Digital twin (DT) technology is recognized for its transformative potential to enhance efficiency in the construction process. However, the full potential of DT in construction practices remains largely unrealised.
Jiachen Sun, Atasya Osmadi, Terh Jing Khoo, Qinghua Liu, Yi Zheng, Shan Liu, Yiwen Xu   +6 more
doaj   +1 more source

Process Transparency on Construction Sites: Examples from Construction Companies in Brazil [PDF]

Process transparency is the core concept in Visual Management (VM), which is one of the founding blocks of the Toyota Production System. This paper presents the preliminary results of a collaborative research conducted between Brazil and the UK, as part ...
Alves, Thais, Formoso, Carlos, Koskela, Lauri, Mota, Bruno, Neto, José Barros, Tezel, Algan, Tzortzopoulos, Patricia, Viana, Daniela   +7 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modifications of the Stress-State of Cable-Stayed Bridges due to Staggered Construction of their Superstructure

The Baltic Journal of Road and Bridge Engineering, 2014
In current practice, the effects of the evolutionary erection of cable-stayed bridge superstructure are rarely included into the simulation of its tensioning process. In fact, stay forces in service are usually defined in early stages of design, when the
Jose Antonio Lozano-Galant, Lidia Ruiz-Ripoll, Ignacio Payá-Zaforteza, José Turmo   +3 more
doaj   +1 more source