Results 111 to 120 of about 4,778,092 (301)
Identifying higher capability maturity KPAs of construction organisations; Model refinement through expert interviews [PDF]
Process improvement has been identified as a mechanism of achieving the much needed performance improvements within the construction industry. Despite the concerns of being an industry with unique characteristics, construction has borrowed some process ...
Amaratunga, Dilanthi +2 more
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Legal Aspects of Architecture, Engineering and the Construction Process by Justin Sweet [PDF]
, 1971 Syftet med detta examensarbete är att ta reda på vilken kunskap lärare har om undervisning i läsförståelse, hur lärare på lågstadiet beskriver sin undervisning men även hur läsundervisningen förändras efter att eleven knäckt läskoden och kommit igång med
Griffin, Harry L., Jr.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Baltic Journal of Road and Bridge Engineering, 2014 In current practice, the effects of the evolutionary erection of cable-stayed bridge superstructure are rarely included into the simulation of its tensioning process. In fact, stay forces in service are usually defined in early stages of design, when the
Jose Antonio Lozano-Galant +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Defining concurrent processes constructively
Theoretical Computer Science, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
UK construction processes and IT adoptability: Learning form other industries [PDF]
Process improvement has been identified as a mechanism of achieving the desired performance improvements of the UK construction industry. During the recent past, researches within UK construction process improvement research paradigm have been influenced
Amaratunga, Dilanthi +2 more
core