Results 91 to 100 of about 4,778,092 (301)

Cost Escalation in Nuclear Power [PDF]

, 1978
This report is concerned with the escalation of capital costs of nuclear central station power plants between the early 1960s and the present. The report presents an historical overview of the development of the nuclear power industry and cost escalation
Montgomery, W. David, Quirk, James P.
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

a variational approach to niche construction [PDF]

, 2018
In evolutionary biology, niche construction is sometimes described as a genuine evolutionary process whereby organisms, through their activities and regulatory mechanisms, modify their environment such as to steer their own evolutionary trajectory, and ...
Campbell, John, Constant, Axel, Friston, Karl, Ramstead, Maxwell, Veissière, Samuel   +4 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Digital Twin Success Factors and Their Impact on Efficiency, Energy, and Cost Under Economic Strength: A Structural Equation Modeling and XGBoost Approach

Buildings
Digital twin (DT) technology is recognized for its transformative potential to enhance efficiency in the construction process. However, the full potential of DT in construction practices remains largely unrealised.
Jiachen Sun, Atasya Osmadi, Terh Jing Khoo, Qinghua Liu, Yi Zheng, Shan Liu, Yiwen Xu   +6 more
doaj   +1 more source

External Prestressing Bridge Reinforcement Technology Review

MATEC Web of Conferences, 2015
Externally prestressed bridge can not only limit and reduce the cracks and deformation of the structure, improve the rigidity and bearing capacity of structure, improve the stress state of structure, but also have less interference for bridge operation ...
Zhu Hanbing, Yang Yaxun, Fan Weiya
doaj   +1 more source

Analysis of changes in cotton moisture under the influence of infrared (IR) radiation [PDF]

BIO Web of Conferences
Current cotton drying technology has a negative impact on product quality due to the use of high temperatures and very low energy efficiency. In the literature on the research on their elimination, information on heat generation from fuel by traditional ...
Kayumov Abdul-Malik, Eshmatov Bohodir, Rakhmatov Gulomjon   +2 more
doaj   +1 more source

Le talent discret des mosaïstes antiques. Une étude de cas relative aux méandres de svastikas

Journal of Mosaic Research, 2020
The Discreet Talent of Ancient Mosaicists. A Case Study Relating to Swastika-Meanders The talent of the ancient mosaicists who carried out pavements with geometrical patterns is often unsung, and to some extent underestimated, with regard to the ...
Bernard PARZYSZ
doaj   +1 more source