Results 111 to 120 of about 24,748,961 (324)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A System Dynamics Model for Risk Analysis during Project Construction Process
, 2014 Risk analysis is an important part for many large and medium-sized construction projects; mean-while the correct and reasonable project risk analysis can be conducive to risk management. Based on the results of the case study supplemented by a literature
Jiangping Wan, Yaqiong Liu
semanticscholar +1 more source
Arguing satisfaction of security requirements [PDF]
, 2006 This chapter presents a process for security requirements elicitation and analysis, based around the construction of a satisfaction argument for the security of a system. The process starts with the enumeration of security goals based on assets in the
Haley, Charles B. +3 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Triaxial tests on frozen ground: formulation and modelling [PDF]
, 2013 Artificial Ground Freezing (AGF) is a controllable process that can be used by engineers to stabilise temporarily the ground, provide structural support and/or exclude groundwater from an excavation until construction of the final lining provides ...
Casini, Francesca +3 more
core
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
International Conference on Human Factors in Computing SystemsSupport for story character construction is as essential as characters are for stories. Building upon past research on early character construction stages, we explore how conversation with chatbot avatars embodying characters powered by more recent ...
Hua Xuan Qin +4 more
semanticscholar +1 more source
Leadership Behaviour and Worker Performance in the Nigerian Construction Industry [PDF]
, 2019 Leadership is a dynamic process in which an individual influence other to contribute to the achievement of an assigned task. This paper investigates leadership behaviour and its impact on construction workers’ performance in Lagos, Nigeria.
Adebiyi, John +2 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Interpretation-Construction Distinction [PDF]
, 2010 The interpretation-construction distinction, which marks the difference between linguistic meaning and legal effect, is much discussed these days. I shall argue that the distinction is both real and fundamental – that it marks a deep difference in two ...
Solum, Lawrence B.
core +2 more sources