Results 61 to 70 of about 7,484,663 (307)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

RISK MANAGEMENT IN CONSTRUCTION PROJECTS

open access: yesTechnological and Economic Development of Economy, 2015
Risk management is an important field of construction industry and has gained more importance internationally due to the latest researches carried out on a large scale. However, this relatively new field requires more attention to bring some benefit. Construction projects are facing a number of risks which have negative effects on project objects such ...
Iqbal, Shahid   +4 more
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

How Does the Five-Day Work Week Impact Labour Productivity? Exploring the Perceptions of Australian Construction Workers

open access: yesBuildings
Construction is a long-hours industry in which people often work a six-day week. This research examined the extent to which shifting to a five-day week schedule impacts labour productivity in construction projects. Five construction projects in Australia
Michelle Turner   +2 more
doaj   +1 more source

Strategies to Minimise the Impact of COVID-19 on the Construction Industry: A Case Study of Construction Site Clusters in Malaysia

open access: yesConstruction Economics and Building, 2022
Malaysia has seen the third wave of infection since the start of the global COVID-19 pandemic, with approximately 103 construction sites involving over 14,667 workers reported from April 2020 to February 2021.
Farah Salwati Ibrahim   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Contemporary Review of Anti-Corruption Measures in Construction Project Management

open access: yesProject Management Journal, 2018
This study reviews the anti-corruption measures (ACMs) developed to mitigate the pervasiveness of corruption in construction project management (CPM). Using a two-stage methodological process to identify the relevant publications needed, 39 unique ACMs ...
E. Owusu   +4 more
semanticscholar   +1 more source

Evaluation of the Power Generation Impact for the Mobility of Battery Electric Vehicles

open access: yesEnergies, 2023
European institutions have decided to ban the sale of Internal Combustion Vehicles (ICEVs) in the EU from 2035. This opens a possible scenario in which, in the not-too-distant future, all vehicles circulating in Europe are likely to be Battery Electric ...
Javier Rey, Lázaro V. Cremades
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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