Results 51 to 60 of about 278,888 (316)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
EVALUATION METHODS FOR CONSTRUCTION PROJECTS
JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT, 2009 Financial evaluation methods such as Net Present Value (NPV) and Internal Rate of Return (IRR) are not fully adequate for accounting three practical aspects of construction projects: reinvestment rate, actual amount of required investment, and firm available funds.
Park, Moonseo +3 more
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Frontiers in WaterThe ecological degradation and groundwater level decline caused by runoff reduction in arid inland river basins are becoming increasingly severe under the dual pressures of global climate change and human activities.
Wenxin Li +3 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Hard, soft or lean? Planning on medium size construction projects
, 1999 In a paper presented to the 11th Annual ARCOM Conference, Johansen examined the way that managers and planners in medium sized construction projects plan in a flexible manner.
Greenwood, David, Johansen, Eric
core
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Advances in Civil EngineeringThis paper provides a comprehensive review of the use of life cycle cost assessment (LCCA) and life cycle assessment (LCA) methods for evaluating the sustainability and costs of using recycled materials in asphalt pavement rehabilitation projects.
Abbas F. Jasim +2 more
doaj +1 more source
BuildingsThe risk–benefit analysis of ERP implementation is worth investigating to optimize the efficiency of ERP deployment in the construction sector. This study investigates the factors affecting the dissipation of ERP through diffusion models in developing ...
Marie-Belle Boutros +3 more
doaj +1 more source
SHS Web of Conferences, 2017 Energy saving potential is quite huge in the most sectors of the national economy, particularly in housing and utilities and industry. Due to this, energy efficiency increase at the enterprises of housing and utilities and industry through the energy ...
Borisova Natalia +2 more
doaj +1 more source