Results 91 to 100 of about 1,575,291 (297)

The application of virtual reality technology in architectural pedagogy for building constructions

open access: yesAlexandria Engineering Journal, 2019
The recent development in information technology has huge opportunities to improve the architectural education in terms of methodologies, strategies and tools.
Ahmad K. Bashabsheh   +2 more
doaj   +1 more source

Knowledge Construction of 3D Geometry Concepts and Processes Within a Virtual Reality Learning Environment [PDF]

open access: yes, 2004
A consensus has emerged within the mathematics education community about the limitations of traditional approaches for teaching and learning 3D geometry.
Nason, Rodney, Yeh, Andy
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Public Libraries and Social Construction of Reality [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2010
In the present paper, subsequent to expressing the theoretical approaches which explain the episteme-methodological basis of encountering and interpreting the social events, and by taking advantage of the social constructivism approach which culminated ...
Ahmad Parsazadeh, Mehdi Shaghaghi
doaj  

Hard, soft or lean? Planning on medium size construction projects [PDF]

open access: yes, 1999
In a paper presented to the 11th Annual ARCOM Conference, Johansen examined the way that managers and planners in medium sized construction projects plan in a flexible manner.
Greenwood, David, Johansen, Eric
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Wittgenstein on the foundations of language : A non foundational narration [PDF]

open access: yes, 2009
The primary objective of this paper is to show that for later Wittgenstein, language cannot be based on a pre-linguistic foundation. Following closely on the tracks of the philosopher, it argues that none of the proposed foundations that are claimed to ...
Mitra, Enakshi
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Exploring Virtual Reality and Digital Twin Technologies for Sustainable Construction Training in Higher Education [PDF]

open access: yesE3S Web of Conferences
The integration of Virtual Reality (VR) and Digital Twin (DT) technologies into construction training exemplifies a groundbreaking approach to teaching in sustainable building practices.
Adilov Zarifjon   +5 more
doaj   +1 more source

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