Results 51 to 60 of about 1,575,291 (297)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Embodiment of the Interpretant in a Sign: Reconsider the Concept of a Sign as a Factor of Social Construction in the Frame of Embodied and Disembodied Mind [PDF]

open access: yesStudia Warmińskie, 2017
Social reality is semiotically constructed through a sign and sign relations as the mechanism of mediation and creation of “being together”. Social reality is in a constant creative process of dynamic change.
Kovchak Volodymyr
doaj  

Construction Hazard Investigation Leveraging Object Anatomization on an Augmented Photoreality Platform

open access: yesApplied Sciences, 2019
Hazard investigation education plays a crucial role in equipping students with adequate knowledge and skills to avoid or eliminate construction hazards at workplaces.
Hai Chien Pham   +4 more
doaj   +1 more source

Constructing a Social Problem: The Press and the Environment [PDF]

open access: yes, 1979
The U. S. daily press might seem to be in a strategic position to function as a claims-maker in the early construction of a social problem. But in the case of the manufacture of environmentalism as a social reality in the 1960\u27s and 70\u27s, the press
Griffin, Robert J.   +2 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Spatial Transfiguration: Anamorphic Mixed-Reality in the Virtual Reality Panorama [PDF]

open access: yes, 2007
Spatial illusion and immersion was achieved in Renaissance painting through the manipulation of linear perspective’s pictorial conventions and painterly technique.
Brisbin, Christopher
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A Comprehensive Framework for Integrating Extended Reality into Lifecycle-Based Construction Safety Management

open access: yesApplied Sciences
Construction remains one of the most hazardous industries, with high accident rates driven by insufficient planning, coordination, and safety training.
Felipe Muñoz-La Rivera   +3 more
doaj   +1 more source

The Mystery of Capital and the Construction of Social Reality [PDF]

open access: yes, 2008
John Searle’s The Construction of Social Reality and Hernando de Soto’s The Mystery of Capital shifted the focus of current thought on capital and economic development to the cultural and conceptual ideas that underpin market economies and that are taken
Ehrlich, Isaac   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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