Results 91 to 100 of about 5,489,361 (292)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Improving construction materials management practices in construction sites [PDF]

open access: yes, 2017
Construction Materials Management is a vital function for improving productivity in construction projects. Poor materials management can often affect the overall construction time, quality and budget.
Ahmed, Fuad Hassan
core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A linear regression modelling of the relationship between initial estimated and final achieved construction time in South Africa

open access: yesActa Structilia, 2012
The estimation of contract completion time has always been inaccurate despite there being a need for certainty regarding the completion of projects. This article reports on an investigation of the relationship between initial and final contract time with
Olatunji Ayodeji Aiyetan   +2 more
doaj  

Five-Year Epidemiological Study and Estimation of Accidents Distribution in Construction Industry Workers in Yazd City by the Year 2011 by Applying Time Series Model [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2009
Background & Aims: Occupational accidents are known as one of the most important causes of disabilities and mortality in developed and developing countries.
A Bahrampour   +2 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A time marker instrument for kinematics movement studies: a development of previous versions

open access: yesSemina: Ciências Exatas e Tecnológicas, 2009
This article presents a time marker to study movements in kinematics. It contributes to elaborate a version of time marker which low cost and more efficient in comparison with the marker presented in another work as well as the earlier commercial version.
Carlos Eduardo Laburú   +1 more
doaj  

Development of methodology for time management of construction projects

open access: yesИнженерно-строительный журнал, 2016
This article dwells upon the issues of providing project timely completion as well as key project milestones. In many cases project deadline exceed leads to catastrophic outcomes for the aims and results of the project.
S. V. Bovteev, S.V. Kanyukova
doaj   +1 more source

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