Results 81 to 90 of about 5,489,361 (292)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Time and Cost Overrun in Construction Projects of Pakistan
Pakistan Journal of Engineering & Technology, 2019 According to this research, time and cost overruns in construction initiatives of Pakistan. So, carried out the qualitative questionnaire survey to collect the data for each time and cost invades.
Asad Iqbal +10 more
doaj +3 more sources
Automated Counting of Steel Construction Materials: Model, Methodology, and Online Deployment
BuildingsConstruction material management is crucial for promoting intelligent construction methods. At present, the manual inventory of materials is inefficient and expensive.
Jun Chen +4 more
doaj +1 more source
Modeling of the Time Structure of Construction Processes Using Neural Networks
Organization, Technology and Management in Construction: An International Journal, 2017 The aim of this research is to develop a methodology for calculating the standard time using neural networks. The paper presents research questions and proposes a methodology.
Petlíková Kateřina, Jarský Čeněk
doaj +1 more source
Polynomial-Time Space-Optimal Silent Self-Stabilizing Minimum-Degree Spanning Tree Construction [PDF]
, 2014 Motivated by applications to sensor networks, as well as to many other areas, this paper studies the construction of minimum-degree spanning trees. We consider the classical node-register state model, with a weakly fair scheduler, and we present a space ...
Blin, Lélia, Fraigniaud, Pierre
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Construction: Notes on Qualitative Time and Space
Pensamiento. Revista de Investigación e Información Filosófica, 2015 The conceptual definition of time and space has given rise to some difficulties in classical philosophy. These difficulties worsen with reference to time, which is presented as an «obscure idea». The root of the problem lies in considering time and space
José Antón Pacheco
doaj
Simulation of virtual time norms for technological processes
Journal of Business Economics and Management, 2003 The methodology presented in the article is based on the simulation of technological process duration, restricting on the available information about total duration of complex technological process in the conditions when there are no possibilities to ...
Romualdas Tamošaitis +1 more
doaj +1 more source
Waste Cooking Oil-Modified Epoxy Asphalt Rubber Binders with Improved Compatibility and Extended Allowable Construction Time. [PDF]
Molecules, 2022 Gong J +6 more
europepmc +1 more source